Jolkinolide B

Modify Date: 2024-01-06 11:38:14

Jolkinolide B Structure
Jolkinolide B structure
Common Name Jolkinolide B
CAS Number 37905-08-1 Molecular Weight 330.418
Density 1.3±0.1 g/cm3 Boiling Point 497.1±45.0 °C at 760 mmHg
Molecular Formula C20H26O4 Melting Point N/A
MSDS N/A Flash Point 219.8±28.8 °C

 Use of Jolkinolide B


Jolkinolide B, a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud, is known to induce apoptosis in cancer cells[1].

 Names

Name 1,4-dibutyl-N-(2,6-dimethylphenyl)piperazine-2-carboxamide,nitrous acid
Synonym More Synonyms

 Jolkinolide B Biological Activity

Description Jolkinolide B, a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud, is known to induce apoptosis in cancer cells[1].
Related Catalog
Target

IC50: apoptosis[1]

References

[1]. Wang, J., Zhou, Y., Bai, X. et al. Jolkinolide B from Euphorbia fischeriana Steud induces apoptosis in human leukemic U937 cells through PI3K/Akt and XIAP pathways. Mol Cells 32, 451–457 (2011).

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 497.1±45.0 °C at 760 mmHg
Molecular Formula C20H26O4
Molecular Weight 330.418
Flash Point 219.8±28.8 °C
Exact Mass 330.183105
PSA 51.36000
LogP 3.24
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.593
Storage condition 2-8℃

 Synonyms

(4aR,6aS,7aR,10aR,11aR,11bR,11cR)-4,4,8,11c-Tetramethyl-1,2,3,4,4a,5,6,11a,11b,11c-decahydrobisoxireno[3,4:1,10a]phenanthro[3,2-b]furan-9(7aH)-one
2-Piperazinecarboxamide,1,4-dibutyl-N-(2,6-dimethylphenyl)-,dinitrate
1,4-dibutyl-n-(2,6-dimethylphenyl)piperazine-2-carboxamide ntrite(1:2)
jokiolide B
jolkinolide B
Bisoxireno[3,4:1,10a]phenanthro[3,2-b]furan-9(7aH)-one, 1,2,3,4,4a,5,6,11a,11b,11c-decahydro-4,4,8,11c-tetramethyl-, (4aR,6aS,7aR,10aR,11aR,11bR,11cR)-
2-Piperazinecarboxanilide,1,4-dibutyl-2',6'-dimethyl-,dinitrate
1,4-dibutyl-N-(2,6-dimethylphenyl)piperazine-2-carboxamide
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