Antitubercular agent-30

Modify Date: 2024-08-13 21:28:03

Antitubercular agent-30 Structure
Antitubercular agent-30 structure
Common Name Antitubercular agent-30
CAS Number 384857-54-9 Molecular Weight 262.28
Density 1.421±0.06 g/cm3(Predicted) Boiling Point 517.5±40.0 °C(Predicted)
Molecular Formula C12H10N2O3S Melting Point 125-127 °C
MSDS N/A Flash Point N/A

 Use of Antitubercular agent-30


Antitubercular agent-30 is an antibacterial agent against Mycobacterium tuberculosis (MIC=50 μg/mL). Antitubercular agent-30 has little cytotoxic effect on murine macrophage cells (LD85=~100 μg/mL)[1].

 Names

Name N-(4-nitrophenyl)-2-thiophen-2-ylacetamide

 Antitubercular agent-30 Biological Activity

Description Antitubercular agent-30 is an antibacterial agent against Mycobacterium tuberculosis (MIC=50 μg/mL). Antitubercular agent-30 has little cytotoxic effect on murine macrophage cells (LD85=~100 μg/mL)[1].
Related Catalog
In Vitro Antitubercular agent-30 (compound 16) (0.1-100 μg/mL; 18 h) 的浓度低于 10 μg/mL 时,对小鼠巨噬细胞无细胞毒作用[1]。
References

[1]. Silva Lourenço MC, et al. Synthesis and biological evaluation of N-(aryl)-2-thiophen-2-ylacetamides series as a new class of antitubercular agents. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6895-8.  

 Chemical & Physical Properties

Density 1.421±0.06 g/cm3(Predicted)
Boiling Point 517.5±40.0 °C(Predicted)
Melting Point 125-127 °C
Molecular Formula C12H10N2O3S
Molecular Weight 262.28
Storage condition -20°C