SNAP-7941
Modify Date: 2024-01-10 10:51:14
SNAP-7941 structure
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Common Name | SNAP-7941 | ||
|---|---|---|---|---|
| CAS Number | 387825-78-7 | Molecular Weight | 613.652 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C33H41F2N5O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SNAP-7941SNAP-7941 is a selective, high-affinity, and competitive MCH1 receptor (MCH1-R) antagonist with Ki of 15 nM; inhibits food intake stimulated by central administration of MCH, reduces consumption of palatable food, decreases in body weight in rats with diet-induced obesity; also produces effects similar to clinically used antidepressants and anxiolytics in animal models of depression/anxiety. Obesity Discontinued |
| Name | SNAP-7941 |
|---|---|
| Synonym | More Synonyms |
| Description | SNAP-7941 is a selective, high-affinity, and competitive MCH1 receptor (MCH1-R) antagonist with Ki of 15 nM; inhibits food intake stimulated by central administration of MCH, reduces consumption of palatable food, decreases in body weight in rats with diet-induced obesity; also produces effects similar to clinically used antidepressants and anxiolytics in animal models of depression/anxiety. Obesity Discontinued |
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| References | References 1. Borowsky B, et al. Nat Med. 2002 Aug;8(8):825-30. 2. Basso AM, et al. Eur J Pharmacol. 2006 Jul 1;540(1-3):115-20. 3. Millan MJ, et al. Int J Neuropsychopharmacol. 2008 Dec;11(8):1105-22. View Related Products by Target Melanin-concentrating Hormone Receptor (MCHR) Obesity |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C33H41F2N5O6 |
| Molecular Weight | 613.652 |
| Exact Mass | 613.271179 |
| LogP | 2.47 |
| Index of Refraction | 1.572 |
| Methyl (4S)-3-({3-[4-(3-acetamidophenyl)-1-piperidinyl]propyl}carbamoyl)-4-(3,4-difluorophenyl)-6-(methoxymethyl)-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate |
| SNAP-7941 |
| 5-Pyrimidinecarboxylic acid, 1-[[[3-[4-[3-(acetylamino)phenyl]-1-piperidinyl]propyl]amino]carbonyl]-6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-, methyl ester, (6S)- |
| methyl (4S)-3-[(3-{4-[3-(acetylamino)phenyl]piperidin-1-yl}propyl)carbamoyl]-4-(3,4-difluorophenyl)-6-(methoxymethyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |