Isodeoxyelephantopin

Modify Date: 2024-01-08 17:14:48

Isodeoxyelephantopin Structure
Isodeoxyelephantopin structure
Common Name Isodeoxyelephantopin
CAS Number 38927-54-7 Molecular Weight 344.358
Density 1.3±0.1 g/cm3 Boiling Point 584.3±50.0 °C at 760 mmHg
Molecular Formula C19H20O6 Melting Point 150-153℃
MSDS USA Flash Point 258.1±30.2 °C

 Use of Isodeoxyelephantopin


Isodeoxyelephantopin is a sesquiterpene lactone isolated from Elephantopus scaber. Isodeoxyelephantopin induces ROS generation, suppresses NF-κB activation. Isodeoxyelephantopin also modulates LncRNA expression and exhibit activities against breast cancer[1][2].

 Names

Name (2-cyanophenyl)methyl acetate
Synonym More Synonyms

 Isodeoxyelephantopin Biological Activity

Description Isodeoxyelephantopin is a sesquiterpene lactone isolated from Elephantopus scaber. Isodeoxyelephantopin induces ROS generation, suppresses NF-κB activation. Isodeoxyelephantopin also modulates LncRNA expression and exhibit activities against breast cancer[1][2].
Related Catalog
In Vitro Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop.
References

[1]. Verma SS, et al. Isodeoxyelephantopin, a Sesquiterpene Lactone Induces ROS Generation, Suppresses NF-κB Activation, Modulates LncRNA Expression and Exhibit Activities Against Breast Cancer. Sci Rep. 2019 Nov 29;9(1):17980.

[2]. Yunna Kim, et al. Treatment of Hominis placenta pharmacopuncture for a patient with mild neurocognitive disorder: Case report. J Pharmacopuncture. 2019 Dec; 22(4): 279–283.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 584.3±50.0 °C at 760 mmHg
Melting Point 150-153℃
Molecular Formula C19H20O6
Molecular Weight 344.358
Flash Point 258.1±30.2 °C
Exact Mass 344.125977
PSA 78.90000
LogP 1.51
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.556
Storage condition ?20°C

 Safety Information

Hazard Codes Xi
RIDADR NONH for all modes of transport

 Synonyms

(3S,4R,8R,9Z,12S)-10-Methyl-5-methylene-6,14-dioxo-7,13-dioxatricyclo[10.2.1.0]pentadeca-1(15),9-dien-3-yl methacrylate
2-Propenoic acid, 2-methyl-, (3aR,4S,9S,11Z,12aR)-2,3,3a,4,5,9,10,12a-octahydro-11-methyl-3-methylene-2,7-dioxo-7H-9,6-methenofuro[2,3-f]oxacycloundecin-4-yl ester
Isodeoxyelephantopin
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