Dehydrovomifoliol

Modify Date: 2024-01-11 10:31:41

Dehydrovomifoliol Structure
Dehydrovomifoliol structure
Common Name Dehydrovomifoliol
CAS Number 39763-33-2 Molecular Weight 222.28
Density 1.1±0.1 g/cm3 Boiling Point 367.4±42.0 °C at 760 mmHg
Molecular Formula C13H18O3 Melting Point N/A
MSDS N/A Flash Point 190.2±24.4 °C

 Use of Dehydrovomifoliol


Dehydrovomifoliol is a AKT/mTOR dual inhibitor. Dehydrovomifoliol reduces lipid accumulation and lipogenesis by inhibiting the AKT/mTOR signaling pathway. Dehydrovomifoliol is used in nonalcoholic fatty liver disease research (NAFLD) .

 Names

Name (6S)-dehydrovomifoliol
Synonym More Synonyms

 Dehydrovomifoliol Biological Activity

Description Dehydrovomifoliol is a AKT/mTOR dual inhibitor. Dehydrovomifoliol reduces lipid accumulation and lipogenesis by inhibiting the AKT/mTOR signaling pathway. Dehydrovomifoliol is used in nonalcoholic fatty liver disease research (NAFLD) .
Related Catalog
References

[1]. MaJ, et al. Dehydrovomifoliol Alleviates Nonalcoholic FattyLiver Disease via the E2F1/AKT/mTOR Axis: Pharmacophore Modeling and MolecularDocking Study. Evid Based Complement Alternat Med. 2023 Feb 1;2023:9107598.  

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 367.4±42.0 °C at 760 mmHg
Molecular Formula C13H18O3
Molecular Weight 222.28
Flash Point 190.2±24.4 °C
Exact Mass 222.125595
LogP 0.73
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.554
Storage condition 2-8℃

 Synonyms

(4S)-4-Hydroxy-3,5,5-trimethyl-4-[(1E)-3-oxo-1-buten-1-yl]-2-cyclohexen-1-one
(6S)-dehydrovomifoliol
2-Cyclohexen-1-one, 4-hydroxy-3,5,5-trimethyl-4-[(1E)-3-oxo-1-buten-1-yl]-, (4S)-
Dehydrovomifoliol