MDL 12330A hydrochloride

Modify Date: 2024-01-10 01:33:27

MDL 12330A hydrochloride Structure
MDL 12330A hydrochloride structure
Common Name MDL 12330A hydrochloride
CAS Number 40297-09-4 Molecular Weight 377.01
Density N/A Boiling Point 515ºC at 760 mmHg
Molecular Formula C23H37ClN2 Melting Point 148 - 152 °C
MSDS USA Flash Point 265.2ºC

 Use of MDL 12330A hydrochloride


MDL12330A (RMI12330A) is an adenyl cyclase inhibitor. MDL12330A inhibits the vasopressin action on the short-circuit current (SCC). MDL12330A is also an inhibitor of cAMP phosphodiesterase[1].

 Names

Name N-(2-phenylcyclopentyl)-1-azacyclotridecen-2-amine,hydrochloride
Synonym More Synonyms

 MDL 12330A hydrochloride Biological Activity

Description MDL12330A (RMI12330A) is an adenyl cyclase inhibitor. MDL12330A inhibits the vasopressin action on the short-circuit current (SCC). MDL12330A is also an inhibitor of cAMP phosphodiesterase[1].
Related Catalog
References

[1]. Lippe C, et al. Actions of vasopressin and isoprenaline on the ionic transport across the isolated frog skin in the presence and the absence of adenyl cyclase inhibitors MDL12330A and SQ22536. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1991;99(1-2):209-11.  

 Chemical & Physical Properties

Boiling Point 515ºC at 760 mmHg
Melting Point 148 - 152 °C
Molecular Formula C23H37ClN2
Molecular Weight 377.01
Flash Point 265.2ºC
Exact Mass 376.26500
PSA 24.39000
LogP 6.85390
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles27

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Stimulating effects of dopamine on chloride transport across the rat caudal epididymal epithelium in culture.

Biol. Reprod. 80(1) , 13-23, (2009)

The present study investigated the effects of dopamine on chloride transport across cultured rat caudal epididymal epithelium. The results showed that dopamine induced a biphasic short-circuit current...

Dopamine D1 receptors mediate dopamine-induced duodenal epithelial ion transport in rats.

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Dopamine (DA) is synthesized in gastrointestinal epithelial cells and performs important regulatory effects on the duodenal mucosa. However, the underlying mechanism remains largely unknown. The prese...

 Synonyms

MFCD00210204
cis-N-(2-Phenylcyclopentyl)-azacyclotridec-1-en-2-amine hydrochloride
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