Tyrosine, 3-fluoro-

Modify Date: 2024-01-11 14:37:11

Tyrosine, 3-fluoro- Structure
Tyrosine, 3-fluoro- structure
Common Name Tyrosine, 3-fluoro-
CAS Number 403-90-7 Molecular Weight 199.17900
Density 1.421g/cm3 Boiling Point 362.4ºC at 760mmHg
Molecular Formula C9H10FNO3 Melting Point 276-280ºC
MSDS Chinese USA Flash Point 172.9ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Tyrosine, 3-fluoro-


2-Amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid is a tyrosine derivative[1].

 Names

Name 3-fluorotyrosine
Synonym More Synonyms

 Tyrosine, 3-fluoro- Biological Activity

Description 2-Amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid is a tyrosine derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

 Chemical & Physical Properties

Density 1.421g/cm3
Boiling Point 362.4ºC at 760mmHg
Melting Point 276-280ºC
Molecular Formula C9H10FNO3
Molecular Weight 199.17900
Flash Point 172.9ºC
Exact Mass 199.06400
PSA 83.55000
LogP 1.18600
Vapour Pressure 6.94E-06mmHg at 25°C
Index of Refraction 1.591
Storage condition 2-8°C
Stability Stable. Incompatible with strong reducing agents, strong oxidizing agents.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YP2660000
CHEMICAL NAME :
Tyrosine, 3-fluoro-, DL-
CAS REGISTRY NUMBER :
403-90-7
BEILSTEIN REFERENCE NO. :
3204804
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H10-F-N-O3
MOLECULAR WEIGHT :
199.20
WISWESSER LINE NOTATION :
QVYZ1R DQ CF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 68,1671,1946
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9900 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 155,135,1967

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H332
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn,T
Risk Phrases 20/21/22
Safety Phrases S24/25
RIDADR UN 3276
WGK Germany 3
RTECS YP2660000
Packaging Group II
Hazard Class 6.1
HS Code 2922509090

 Synthetic Route

~%

Tyrosine, 3-fluoro- Structure

Tyrosine, 3-fluoro-

CAS#:403-90-7

Literature: Schiemann; Winkelmueller Journal fuer Praktische Chemie (Leipzig), 1932 , vol. <2> 135, p. 101,113 Full Text Show Details Niemann; Benson; Mead Journal of the American Chemical Society, 1941 , vol. 63, p. 2204,2208

~%

Tyrosine, 3-fluoro- Structure

Tyrosine, 3-fluoro-

CAS#:403-90-7

Literature: Vasdev, Neil; Chirakal, Raman; Ashique, Rezwan; Schrobilgen, Gary J.; Gulenchyn, Karen Journal of Fluorine Chemistry, 2003 , vol. 121, # 1 p. 9 - 14

~%

Tyrosine, 3-fluoro- Structure

Tyrosine, 3-fluoro-

CAS#:403-90-7

Literature: Dibbo,A. et al. Journal of the Chemical Society, 1961 , p. 2645 - 2651

~%

Tyrosine, 3-fluoro- Structure

Tyrosine, 3-fluoro-

CAS#:403-90-7

Literature: Kraft Chemische Berichte, 1951 , vol. 84, p. 150,154

~%

Tyrosine, 3-fluoro- Structure

Tyrosine, 3-fluoro-

CAS#:403-90-7

Literature: Schiemann; Winkelmueller Journal fuer Praktische Chemie (Leipzig), 1932 , vol. <2> 135, p. 101,113

~%

Tyrosine, 3-fluoro- Structure

Tyrosine, 3-fluoro-

CAS#:403-90-7

Literature: Dibbo,A. et al. Journal of the Chemical Society, 1961 , p. 2645 - 2651

~%

Tyrosine, 3-fluoro- Structure

Tyrosine, 3-fluoro-

CAS#:403-90-7

Literature: Kraft Chemische Berichte, 1951 , vol. 84, p. 150,154

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles28

More Articles
Aminoacrylate intermediates in the reaction of Citrobacter freundii tyrosine phenol-lyase.

Biochemistry 45(31) , 9575-83, (2006)

Tyrosine phenol-lyase (TPL) from Citrobacter freundii is a pyridoxal 5'-phosphate (PLP)-dependent enzyme that catalyzes the reversible hydrolytic cleavage of l-Tyr to give phenol and ammonium pyruvate...

Hydrogen bonding in human manganese superoxide dismutase containing 3-fluorotyrosine.

Biophys. J. 89(6) , 4171-9, (2005)

Incorporation of 3-fluorotyrosine and site-specific mutagenesis has been utilized with Fourier transform infrared (FTIR) spectroscopy and x-ray crystallography to elucidate active-site structure and t...

Conformational changes in the crystal structure of rat glutathione transferase M1-1 with global substitution of 3-fluorotyrosine for tyrosine.

J. Mol. Biol. 281(2) , 323-39, (1998)

The structure of the tetradeca-(3-fluorotyrosyl) M1-1 GSH transferase (3-FTyr GSH transferase), a protein in which tyrosine residues are globally substituted by 3-fluorotyrosines has been determined a...

 Synonyms

2-Amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid
MFCD00063075
FLUORTHYRIN
PARDINON
DL-M-FLUOROTYROSINE
ba2745
DL-3-FLUOROTYROSINE
m-fluorotyrosine
m-ftyr
H-3-FLUORO-DL-TYR-OH
EINECS 206-964-0
3-FLUORO-TYROSINE
Tyrosine, 3-fluoro-
rac-3-Fluorotyrosine
M-FLUORO-DL-TYROSINE
3'-fluoro-DL-tyrosine
Top Suppliers:I want be here



Get all suppliers and price by the below link:

Tyrosine, 3-fluoro- suppliers

Tyrosine, 3-fluoro- price