Methoprene

Modify Date: 2024-03-21 14:27:47

Methoprene structure	Common Name	Methoprene
	CAS Number	40596-69-8	Molecular Weight	310.471
	Density	0.9±0.1 g/cm3	Boiling Point	385.7±25.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₃₄O₃	Melting Point	164ºC
	MSDS	Chinese USA	Flash Point	162.4±17.8 °C
	Symbol	GHS07, GHS09	Signal Word	Warning

Use of Methoprene

Methoprene is a juvenile hormone (JH) analog, does not kill insects, acts as an insect growth regulator, interferes with an insect's lifecycle and prevents it from reaching maturity or reproducing, is a biological pesticide.

Name	methoprene
Synonym	More Synonyms

Description	Methoprene is a juvenile hormone (JH) analog, does not kill insects, acts as an insect growth regulator, interferes with an insect's lifecycle and prevents it from reaching maturity or reproducing, is a biological pesticide.
Related Catalog	Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection

Density	0.9±0.1 g/cm3
Boiling Point	385.7±25.0 °C at 760 mmHg
Melting Point	164ºC
Molecular Formula	C₁₉H₃₄O₃
Molecular Weight	310.471
Flash Point	162.4±17.8 °C
Exact Mass	310.250793
PSA	35.53000
LogP	5.63
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.462
Storage condition	0-6°C

Methoprene MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JR1685000

CHEMICAL NAME :: 2,4-Dodecadienoic acid, 11-methoxy-3,7,11-trimethyl-, 1-methylethyl ester, (E,E)-

CAS REGISTRY NUMBER :: 40596-69-8

LAST UPDATED :: 199606

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C19-H34-O3

MOLECULAR WEIGHT :: 310.53

WISWESSER LINE NOTATION :: 1Y1&OV1UY1&1U2Y1&3X1&1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 25 gm/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - somnolence (general depressed activity) Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >210 gm/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3038 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: >210 gm/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 84 mg/kg/3W-I

TOXIC EFFECTS :: Endocrine - changes in adrenal weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: Specific locus test

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Insect - not otherwise specified Ovary

DOSE/DURATION :: 100 umol/L

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 43,1285,1979 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H315-H319-H335-H411
Precautionary Statements	P261-P273-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi: Irritant;N: Dangerous for the environment;
Risk Phrases	R36/37/38
Safety Phrases	26-36-60-61
RIDADR	UN3082 9/PG 3
RTECS	JR1685000
HS Code	2918990090

Precursor 5
CAS#:3613-30-7 UNII:261VCL42SZ CAS#:300786-34-9 isopropyl 2-hyd... CAS#:103768-93-0 isopropyl 11-me... CAS#:616-44-4 3-Methylthiophene
CAS#:4434-77-9 6-bromo-2-methy...
DownStream 0

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Methoprene-tolerant (Met) knockdown in the adult female cockroach, Diploptera punctata completely inhibits ovarian development.

PLoS ONE 9(9) , e106737, (2014)

Independent of the design of the life cycle of any insect, their growth and reproduction are highly choreographed through the action of two versatile hormones: ecdysteroids and juvenile hormones (JH)....

Methyl farnesoate plays a dual role in regulating Drosophila metamorphosis.

PLoS Genet. 11(3) , e1005038, (2015)

Corpus allatum (CA) ablation results in juvenile hormone (JH) deficiency and pupal lethality in Drosophila. The fly CA produces and releases three sesquiterpenoid hormones: JH III bisepoxide (JHB3), J...

Ligand-binding properties of a juvenile hormone receptor, Methoprene-tolerant.

Proc. Natl. Acad. Sci. U. S. A. 108(52) , 21128-33, (2011)

Juvenile hormone (JH) is a sesquiterpenoid of vital importance for insect development, yet the molecular basis of JH signaling remains obscure, mainly because a bona fide JH receptor has not been iden...

Isopropyl (2E,4E)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate

Methoprene

EINECS 254-993-2

MFCD00072475

Isopropyl (2E,4E)-11-Methoxy-3,7,11-trimethyldodeca-trans-2,trans-4-dienoate

UNII:8B830OJ2UX

isopropyl (E,E)-(RS)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate

1-methylethyl (2E,4E)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate

2,4-Dodecadienoic acid, 11-methoxy-3,7,11-trimethyl-, 1-methylethyl ester, (2E,4E)-

1-methylene-indan-4-ol

1-Methylethyl (2E,4E)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate

isopropyl 11-methoxy-3,7,11-trimethyldodeca-2E,4E-1-dienoate

rac-propan-2-yl (2E,4E,7R)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate

juvemon

Isopropyl (2E,4E)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Methoprene
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Methoprene
Price: ￥1898.0/100mg
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Methoprene
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: Methoprene
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: METHOPRENE
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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Price: $96/50mg

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Methoprene

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ACUTE TOXICITY DATA

MUTATION DATA

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