CTP Inhibitor

Modify Date: 2024-01-04 06:34:21

CTP Inhibitor Structure
CTP Inhibitor structure
Common Name CTP Inhibitor
CAS Number 412940-35-3 Molecular Weight 356.73800
Density N/A Boiling Point N/A
Molecular Formula C13H9ClN2O6S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of CTP Inhibitor


CTP inhibitor is a potent and selective CTP inhibitor. CTP inhibitor inhibits the plasma membrane citrate transporter (PMCT)[1].

 Names

Name 4-chloro-3-[(3-nitrophenyl)sulfamoyl]benzoic acid
Synonym More Synonyms

 CTP Inhibitor Biological Activity

Description CTP inhibitor is a potent and selective CTP inhibitor. CTP inhibitor inhibits the plasma membrane citrate transporter (PMCT)[1].
Related Catalog
Target

CTP[1]

References

[1]. Sun J, et al. Mitochondrial and Plasma Membrane Citrate Transporters: Discovery of Selective Inhibitors and Application to Structure/Function Analysis. Mol Cell Pharmacol. 2010; 2(3):101-110.

 Chemical & Physical Properties

Molecular Formula C13H9ClN2O6S
Molecular Weight 356.73800
Exact Mass 355.98700
PSA 137.67000
LogP 4.42420
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319
Precautionary Statements P305 + P351 + P338
Hazard Codes Xi
RIDADR NONH for all modes of transport

 Articles3

More Articles
Mitochondrial and Plasma Membrane Citrate Transporters: Discovery of Selective Inhibitors and Application to Structure/Function Analysis.

Mol. Cell. Pharmacol. 2(3) , 101-110, (2010)

Cytoplasmic citrate is the prime carbon source for fatty acid, triacylglycerol, and cholesterol biosyntheses, and also regulates glucose metabolism via its allosteric inhibition of phosphofructokinase...

Targeting mitochondrial citrate transport in breast cancer cell lines.

Anticancer Agents Med. Chem. 15(3) , 374-81, (2015)

Lipogenesis is considered to be a very important aspect of cancer metabolism and targeting de novo lipid synthesis or related pathways are among novel approaches to treat cancer. Many targets of the p...

Spatio-temporal dynamics of replication and transcription sites in the mammalian cell nucleus.

Chromosoma 117(6) , 553-67, (2008)

To study when and where active genes replicated in early S phase are transcribed, a series of pulse-chase experiments are performed to label replicating chromatin domains (RS) in early S phase and sub...

 Synonyms

4-Chloro-3-[[(3-nitrophenyl)amino]sulfonyl]-benzoic acid
4-Chloro-3-(3-nitro-phenylsulfamoyl)-benzoic acid
CTP Inhibitor