BAM(8-22)

Modify Date: 2024-01-05 20:08:26

BAM(8-22) Structure
BAM(8-22) structure
Common Name BAM(8-22)
CAS Number 412961-36-5 Molecular Weight 1971.20000
Density N/A Boiling Point N/A
Molecular Formula C91H127N25O23S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BAM(8-22)


BAM(8-22), a proteolytically cleaved product of proenkephalin A, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1, and induces scratching in mice in an Mrgpr-dependent manner[1].

 Names

Name Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly
Synonym More Synonyms

 BAM(8-22) Biological Activity

Description BAM(8-22), a proteolytically cleaved product of proenkephalin A, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1, and induces scratching in mice in an Mrgpr-dependent manner[1].
Related Catalog
References

[1]. Parul Sikand, et al. BAM8-22 peptide produces itch and nociceptive sensations in humans independent of histamine release. J Neurosci. 2011 May 18;31(20):7563-7.

 Chemical & Physical Properties

Molecular Formula C91H127N25O23S
Molecular Weight 1971.20000
Exact Mass 1969.93000
PSA 826.78000
LogP 5.47110

 Synonyms

bam8-22