Transketolase-IN-4 structure
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Common Name | Transketolase-IN-4 | ||
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CAS Number | 419547-73-2 | Molecular Weight | 335.78700 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C19H14ClN3O | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Transketolase-IN-4Transketolase-IN-4 is a potent transketolase inhibitor (IC50=3.9 μM). Transketolase-IN-4 inhibits tumor cell proliferation of SW620, LS174T, and MIA PaCa-2. Transketolase-IN-4 is a possible Mycobacterium tuberculosis DXS inhibitor, with an IC50 value of 114.1 μM[1][2]. |
Name | 3-(4-chlorophenyl)-5-benzyl-4H-pyrazolo[1,5-a]pyrimidin-7-one |
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Description | Transketolase-IN-4 is a potent transketolase inhibitor (IC50=3.9 μM). Transketolase-IN-4 inhibits tumor cell proliferation of SW620, LS174T, and MIA PaCa-2. Transketolase-IN-4 is a possible Mycobacterium tuberculosis DXS inhibitor, with an IC50 value of 114.1 μM[1][2]. |
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Related Catalog | |
Target |
IC50: 3.9 μM (Transketolase)[1]; 114.1 μM (Mycobacterium tuberculosis DXS)[2] |
References |
Molecular Formula | C19H14ClN3O |
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Molecular Weight | 335.78700 |
Exact Mass | 335.08300 |
PSA | 50.16000 |
LogP | 3.93380 |