1-(2-Bromoacetoxy)-2,5-pyrrolidinedione
1-(2-Bromoacetoxy)-2,5-pyrrolidinedione structure
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Common Name | 1-(2-Bromoacetoxy)-2,5-pyrrolidinedione | ||
|---|---|---|---|---|
| CAS Number | 42014-51-7 | Molecular Weight | 236.020 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 291.7±42.0 °C at 760 mmHg | |
| Molecular Formula | C6H6BrNO4 | Melting Point | 115-116ºC | |
| MSDS | USA | Flash Point | 130.2±27.9 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 1-(2-Bromoacetoxy)-2,5-pyrrolidinedioneSBA crosslinker, or N-Succinimidyl bromoacetate, is a sulfhydryl (thiol) and amino reactive heterobifunctional protein crosslinking reagent. SBA protein crosslinker is non-cleavable and is among the shortest amine and sulfhydryl reactive crosslinking reagents known with a spacer arm length of only 1.5 Angstroms. SBA Crosslinker is useful for making antibody drug conjugates (ADCs). |
| Name | bromoacetic acid n-hydroxysuccinimide ester |
|---|---|
| Synonym | More Synonyms |
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 291.7±42.0 °C at 760 mmHg |
| Melting Point | 115-116ºC |
| Molecular Formula | C6H6BrNO4 |
| Molecular Weight | 236.020 |
| Flash Point | 130.2±27.9 °C |
| Exact Mass | 234.948013 |
| PSA | 63.68000 |
| LogP | -1.11 |
| Appearance of Characters | powder |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.566 |
| Storage condition | −20°C |
| Water Solubility | acetone: 25 mg/mL |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2925190090 |
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~94%
1-(2-Bromoaceto... CAS#:42014-51-7 |
| Literature: Russian Chemical Bulletin, , vol. 60, # 11 p. 2359 - 2364,6 Izvestiya Akademi Nauk, Seriya Khimicheskaya, , # 11 p. 2312 - 2317,6 Russian Chemical Bulletin, , vol. 60, # 11 p. 2359 - 2364 Izv. Akad. Nauk, Ser. Khim., , # 11 p. 2312 - 2317,6 |
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~%
1-(2-Bromoaceto... CAS#:42014-51-7
Detail
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| Literature: EP1867649 A1, ; Page/Page column 10-11 ; |
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~%
1-(2-Bromoaceto... CAS#:42014-51-7 |
| Literature: Beilstein Journal of Organic Chemistry, , vol. 6, p. 732 - 741 |
| Precursor 4 | |
|---|---|
| DownStream 5 | |
CAS#:607-71-6
CAS#:27667-34-1
CAS#:19063-55-9
CAS#:865817-83-0
CAS#:90834-19-8| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Preparation of peptide-protein immunogens using N-succinimidyl bromoacetate as a heterobifunctional crosslinking reagent.
Anal. Biochem. 155 , 95-102, (1986) Synthetic peptides derived from human fibrin were unidirectionally conjugated to three carrier proteins (bovine serum albumin, bovine alpha-lactalbumin, and keyhole limpet hemocyanin) by a method that... |
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Production of antibodies against degradative neoepitopes in aggrecan.
Methods Mol. Med. 100 , 237-50, (2004) The use of synthetic peptides to generate rabbit polyclonal anticatabolic neoepitope antibodies that can be used to study the presence of defined proteolytic cleavage sites in aggrecan is described. P... |
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Conjugation of synthetic peptides to proteins: quantitation from S-carboxymethylcysteine released upon acid hydrolysis.
Anal. Biochem. 187(1) , 136-40, (1990) A method described here for conjugating synthetic peptides to carrier proteins provides a convenient method for determining peptide-to-carrier protein ratios. N-Bromoacetyl-containing peptides are rea... |
| N-SucciniMidyl BroMoacetate |
| 2,5-Dioxopyrrolidin-1-yl 2-bromoacetate |
| (2,5-dioxopyrrolidin-1-yl) 2-bromoacetate |
| Bromoacetic acid N-hydroxysuccinimide ester |
| 2,5-Pyrrolidinedione, 1-((bromoacetyl)oxy)- |
| MFCD00058571 |
| 1-(2-Bromoacetoxy)pyrrolidine-2,5-dione |
| Bromoacetic Acid N-Succinimidyl Ester |
| 1-(2-Bromoacetoxy)-2,5-pyrrolidinedione |
| N-(Bromoacetoxy)succinimide |
| 2,5-Pyrrolidinedione, 1-[(2-bromoacetyl)oxy]- |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 1-(2-Bromoacetoxy)-2,5-pyrrolidinedione
- Price: Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 1-(2-Bromoacetoxy)-2,5-pyrrolidinedione
- Price: ￥3228.0/500mg ￥848.0/100mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: SBA Crosslinker
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Bromoacetic acid n-hydroxysuccinimide ester
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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