- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 1-(2-Bromoacetoxy)-2,5-pyrrolidinedione
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 1-(2-Bromoacetoxy)-2,5-pyrrolidinedione
- Price: ￥3228.0/500mg ￥848.0/100mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: SBA Crosslinker
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Bromoacetic acid n-hydroxysuccinimide ester
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
42014-51-7
42014-51-7 structure
- Name: 1-(2-Bromoacetoxy)-2,5-pyrrolidinedione
- Chemical Name: bromoacetic acid n-hydroxysuccinimide ester
- CAS Number: 42014-51-7
- Molecular Formula: C6H6BrNO4
- Molecular Weight: 236.020
- Catalog: Chemical reagent Organic reagent Imide
- Create Date: 2018-02-23 08:00:00
- Modify Date: 2024-01-02 18:49:24
-
SBA crosslinker, or N-Succinimidyl bromoacetate, is a sulfhydryl (thiol) and amino reactive heterobifunctional protein crosslinking reagent. SBA protein crosslinker is non-cleavable and is among the shortest amine and sulfhydryl reactive crosslinking reagents known with a spacer arm length of only 1.5 Angstroms. SBA Crosslinker is useful for making antibody drug conjugates (ADCs).
| Name | bromoacetic acid n-hydroxysuccinimide ester |
|---|---|
| Synonyms |
N-SucciniMidyl BroMoacetate
2,5-Dioxopyrrolidin-1-yl 2-bromoacetate (2,5-dioxopyrrolidin-1-yl) 2-bromoacetate Bromoacetic acid N-hydroxysuccinimide ester 2,5-Pyrrolidinedione, 1-((bromoacetyl)oxy)- MFCD00058571 1-(2-Bromoacetoxy)pyrrolidine-2,5-dione Bromoacetic Acid N-Succinimidyl Ester 1-(2-Bromoacetoxy)-2,5-pyrrolidinedione N-(Bromoacetoxy)succinimide 2,5-Pyrrolidinedione, 1-[(2-bromoacetyl)oxy]- |
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 291.7±42.0 °C at 760 mmHg |
| Melting Point | 115-116ºC |
| Molecular Formula | C6H6BrNO4 |
| Molecular Weight | 236.020 |
| Flash Point | 130.2±27.9 °C |
| Exact Mass | 234.948013 |
| PSA | 63.68000 |
| LogP | -1.11 |
| Appearance | powder |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.566 |
| Storage condition | −20°C |
| Water Solubility | acetone: 25 mg/mL |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2925190090 |
|
~94%
42014-51-7 |
| Literature: Russian Chemical Bulletin, , vol. 60, # 11 p. 2359 - 2364,6 Izvestiya Akademi Nauk, Seriya Khimicheskaya, , # 11 p. 2312 - 2317,6 Russian Chemical Bulletin, , vol. 60, # 11 p. 2359 - 2364 Izv. Akad. Nauk, Ser. Khim., , # 11 p. 2312 - 2317,6 |
|
~%
42014-51-7
Detail
|
| Literature: EP1867649 A1, ; Page/Page column 10-11 ; |
|
~%
42014-51-7 |
| Literature: Beilstein Journal of Organic Chemistry, , vol. 6, p. 732 - 741 |
| Precursor 4 | |
|---|---|
| DownStream 5 | |
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |