CASIN structure
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Common Name | CASIN | ||
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CAS Number | 425399-05-9 | Molecular Weight | 306.401 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 577.8±50.0 °C at 760 mmHg | |
Molecular Formula | C20H22N2O | Melting Point | N/A | |
MSDS | USA | Flash Point | 303.3±30.1 °C |
Use of CASINCASIN is a selective GTPase Cdc42 inhibitor with IC50 of 2 uM. In vitro: Treatment with CASIN (5 uM) reduced the elevated level of active Cdc42 observed in aged primitive hematopoietic cells to the level observed in young cells In vivo: Reverses the aging-related and polarity phenotype of aged HSCs to that of young HSCs. |
Name | CASIN |
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Synonym | More Synonyms |
Description | CASIN is a selective GTPase Cdc42 inhibitor with IC50 of 2 uM. In vitro: Treatment with CASIN (5 uM) reduced the elevated level of active Cdc42 observed in aged primitive hematopoietic cells to the level observed in young cells In vivo: Reverses the aging-related and polarity phenotype of aged HSCs to that of young HSCs. |
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Related Catalog | |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 577.8±50.0 °C at 760 mmHg |
Molecular Formula | C20H22N2O |
Molecular Weight | 306.401 |
Flash Point | 303.3±30.1 °C |
Exact Mass | 306.173218 |
LogP | 3.60 |
Appearance of Characters | light yellow solid |
Vapour Pressure | 0.0±1.7 mmHg at 25°C |
Index of Refraction | 1.682 |
Storage condition | -20℃ |
RIDADR | NONH for all modes of transport |
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Ethanol, 2-[(2,3,4,9-tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]- |
2-[(6-Phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)amino]ethanol |