2-Methyl-L-proline

Modify Date: 2024-01-03 09:25:00

2-Methyl-L-proline Structure
2-Methyl-L-proline structure
 Common Name 2-Methyl-L-proline
CAS Number 42856-71-3 Molecular Weight 129.157
Density 1.1±0.1 g/cm3 Boiling Point 241.9±33.0 °C at 760 mmHg
Molecular Formula C6H11NO2 Melting Point 310 °C
MSDS Chinese USA Flash Point 100.1±25.4 °C

 Use of 2-Methyl-L-proline


(S)-2-Methylpyrrolidine-2-carboxylic acid is a proline derivative[1].

 Names

Name (S)-2-Methylpyrrolidine-2-carboxylic acid
Synonym More Synonyms

 2-Methyl-L-proline Biological Activity

Description (S)-2-Methylpyrrolidine-2-carboxylic acid is a proline derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 241.9±33.0 °C at 760 mmHg
Melting Point 310 °C
Molecular Formula C6H11NO2
Molecular Weight 129.157
Flash Point 100.1±25.4 °C
Exact Mass 129.078979
PSA 49.33000
LogP -0.03
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.475
Storage condition -15°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles7

More Articles
Effects of ring contraction on the conformational preferences of α-substituted proline analogs.

Biopolymers 98(2) , 98-110, (2012)

The structural consequences derived from the incorporation of either a methyl or a phenyl group at the α carbon of proline were recently investigated by quantum mechanical calculations (J Org Chem 200...

Beta-turns induced in bradykinin by (S)-alpha-methylproline.

FEBS Lett. 297(3) , 216-20, (1992)

The ability of (S)-alpha-methylproline (alpha-MePro) to stabilise reverse-turn conformations in the peptide hormone bradykinin (BK = Arg1-Pro2-Pro3-Gly4-Phe5-Ser6-Pro7-Phe8-Arg9) has been investigated...

alpha-Methylproline-containing renin inhibitory peptides: in vivo evaluation in an anesthetized, ganglion-blocked, hog renin infused rat model.

J. Med. Chem. 30(3) , 536-41, (1987)

A structure-activity analysis of peptides containing backbone C alpha-methyl modification at the P4 site of the angiotensinogen sequence led to the discovery of potent renin inhibitors with apparent i...

 Synonyms

MFCD01318647
α-Methyl-L-proline
L-Proline, 2-methyl-
2-Methyl-L-proline
(2S)-2-methylpyrrolidine-2-carboxylic acid,hydrochloride
(S)-2-Methyl proline
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