1,1,2-trifluoroethane

DATA ITEMS CITED :

8

MOLECULAR FORMULA :

C2-H3-F3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

25 gm/m3/6H

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - acute pulmonary edema Liver - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :

GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

25 gm/m3/4H

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - acute pulmonary edema Liver - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :

GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

50 mg/m3/4H/17W-I

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - acute pulmonary edema Liver - changes in liver weight Kidney, Ureter, Bladder - other changes

REFERENCE :

GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

50 mg/m3/4H/17W-I

TOXIC EFFECTS :

Behavioral - alteration of classical conditioning Lungs, Thorax, or Respiration - acute pulmonary edema Blood - changes in spleen

REFERENCE :

GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

50 mg/m3/4H/17W-I

TOXIC EFFECTS :

Vascular - BP lowering not characterized in autonomic section Liver - changes in liver weight Endocrine - changes in thyroid weight

REFERENCE :

GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

50 mg/m3/4H/17W-I

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - acute pulmonary edema Liver - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :

GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964