CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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KJ4110010
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CHEMICAL NAME :
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Ethane, 1,1,2-trifluoro-
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CAS REGISTRY NUMBER :
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430-66-0
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BEILSTEIN REFERENCE NO. :
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1731624
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LAST UPDATED :
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199710
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DATA ITEMS CITED :
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8
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MOLECULAR FORMULA :
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C2-H3-F3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LCLo - Lowest published lethal concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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25 gm/m3/6H
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - acute pulmonary edema Liver - other changes Kidney, Ureter, Bladder - other changes
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REFERENCE :
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GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964
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TYPE OF TEST :
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LCLo - Lowest published lethal concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - guinea pig
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DOSE/DURATION :
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25 gm/m3/4H
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - acute pulmonary edema Liver - other changes Kidney, Ureter, Bladder - other changes
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REFERENCE :
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GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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50 mg/m3/4H/17W-I
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - acute pulmonary edema Liver - changes in liver weight Kidney, Ureter, Bladder - other changes
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REFERENCE :
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GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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50 mg/m3/4H/17W-I
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TOXIC EFFECTS :
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Behavioral - alteration of classical conditioning Lungs, Thorax, or Respiration - acute pulmonary edema Blood - changes in spleen
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REFERENCE :
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GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964
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TYPE OF TEST :
-
TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
-
Inhalation
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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50 mg/m3/4H/17W-I
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TOXIC EFFECTS :
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Vascular - BP lowering not characterized in autonomic section Liver - changes in liver weight Endocrine - changes in thyroid weight
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REFERENCE :
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GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964
-
TYPE OF TEST :
-
TCLo - Lowest published toxic concentration
-
ROUTE OF EXPOSURE :
-
Inhalation
-
SPECIES OBSERVED :
-
Rodent - guinea pig
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DOSE/DURATION :
-
50 mg/m3/4H/17W-I
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TOXIC EFFECTS :
-
Lungs, Thorax, or Respiration - acute pulmonary edema Liver - other changes Kidney, Ureter, Bladder - other changes
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REFERENCE :
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GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(10),21,1964
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