SMI481

Modify Date: 2024-01-08 11:42:19

SMI481 Structure
SMI481 structure
Common Name SMI481
CAS Number 432020-20-7 Molecular Weight 363.771
Density 1.4±0.1 g/cm3 Boiling Point 543.3±50.0 °C at 760 mmHg
Molecular Formula C17H15ClFN3O3 Melting Point N/A
MSDS USA Flash Point 282.4±30.1 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of SMI481


NPPM 6748-481 is a selective inhibitor of the yeast phosphatidylinositol transfer protein (PITP) Sec14[1].

 Names

Name (4-Chloro-3-nitrophenyl)[4-(2-fluorophenyl)-1-piperazinyl]methanone
Synonym More Synonyms

 SMI481 Biological Activity

Description NPPM 6748-481 is a selective inhibitor of the yeast phosphatidylinositol transfer protein (PITP) Sec14[1].
Related Catalog
References

[1]. Nile, Aaron H.; Tripathi, Ashutosh; Yuan, Peihua; et al. PITPs as targets for selectively interfering with phosphoinositide signaling in cells. Nature Chemical Biology (2014), 10(1), 76-84.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 543.3±50.0 °C at 760 mmHg
Molecular Formula C17H15ClFN3O3
Molecular Weight 363.771
Flash Point 282.4±30.1 °C
Exact Mass 363.078583
LogP 2.46
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.625

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
RIDADR NONH for all modes of transport

 Synonyms

(4-Chloro-3-nitrophenyl)[4-(2-fluorophenyl)-1-piperazinyl]methanone
Methanone, (4-chloro-3-nitrophenyl)[4-(2-fluorophenyl)-1-piperazinyl]-
MFCD03575351