1-Ethoxy-2,2,2-trifluoroethanol

Modify Date: 2024-01-02 17:58:57

1-Ethoxy-2,2,2-trifluoroethanol Structure
1-Ethoxy-2,2,2-trifluoroethanol structure
Common Name 1-Ethoxy-2,2,2-trifluoroethanol
CAS Number 433-27-2 Molecular Weight 144.092
Density 1.3±0.1 g/cm3 Boiling Point 105.0±0.0 °C at 760 mmHg
Molecular Formula C4H7F3O2 Melting Point N/A
MSDS Chinese USA Flash Point 39.4±0.0 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning

 Names

Name Perfluoroacetaldehyde Ethyl Hemiacetal
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 105.0±0.0 °C at 760 mmHg
Molecular Formula C4H7F3O2
Molecular Weight 144.092
Flash Point 39.4±0.0 °C
Exact Mass 144.039810
PSA 29.46000
LogP 1.73
Vapour Pressure 16.4±0.3 mmHg at 25°C
Index of Refraction 1.342
Storage condition 0-6°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KK9000000
CHEMICAL NAME :
Ethanol, 1-ethoxy-2,2,2-trifluoro-
CAS REGISTRY NUMBER :
433-27-2
BEILSTEIN REFERENCE NO. :
0906797
LAST UPDATED :
199709
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C4-H7-F3-O2
MOLECULAR WEIGHT :
144.11
WISWESSER LINE NOTATION :
FXFFYQO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,1212,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,1212,1970

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning
Hazard Statements H226-H302-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes F:Flammable;Xn:Harmful;
Risk Phrases R11;R22
Safety Phrases S16-S24-S23-S45-S36/37/39
RIDADR UN 1993 3/PG 3
WGK Germany 3
RTECS KK9000000
Packaging Group III
Hazard Class 3
HS Code 2911000000

 Synthetic Route

~61%

1-Ethoxy-2,2,2-trifluoroethanol Structure

1-Ethoxy-2,2,2-...

CAS#:433-27-2

Literature: Lin, Jin-Hong; Xiao, Ji-Chang European Journal of Organic Chemistry, 2011 , # 24 p. 4536 - 4539

~19%

1-Ethoxy-2,2,2-trifluoroethanol Structure

1-Ethoxy-2,2,2-...

CAS#:433-27-2

Literature: Surya Prakash; Jog, Parag V.; Batamack, Patrice T. D.; Olah, George A. Science, 2012 , vol. 338, # 6112 p. 1324 - 1327

~%

1-Ethoxy-2,2,2-trifluoroethanol Structure

1-Ethoxy-2,2,2-...

CAS#:433-27-2

Literature: Fan, Yun-Hua; Haseltine, John Tetrahedron Letters, 1996 , vol. 37, # 52 p. 9279 - 9282

~%

1-Ethoxy-2,2,2-trifluoroethanol Structure

1-Ethoxy-2,2,2-...

CAS#:433-27-2

Literature: Minnesota Mining and Mfg. Co. Patent: US2681370 , 1952 ;

~%

1-Ethoxy-2,2,2-trifluoroethanol Structure

1-Ethoxy-2,2,2-...

CAS#:433-27-2

Literature: Petrov,K.A. et al. Zhurnal Organicheskoi Khimii, 1977 , vol. 13, # 5 p. 943 - 948,866 - 870

 Customs

HS Code 2911000000
Summary 2911000000 acetals and hemiacetals, whether or not with other oxygen function, and their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Articles3

More Articles

Tetrahedron Lett. 33 , 1351, (1992)

Tetrahedron Asymmetry 2 , 235, (1991)

Tetrahedron Lett. 32 , 3823, (1991)

 Synonyms

EINECS 207-087-6
1-Ethoxy-2,2,2-trifluoroethanol
Ethanol, 1-ethoxy-2,2,2-trifluoro-
Trifluoroacetaldehyde Ethyl HeMiacetal
MFCD00000441
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