Lasmiditan hemisuccinate
Modify Date: 2024-01-14 10:18:21
Lasmiditan hemisuccinate structure
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Common Name | Lasmiditan hemisuccinate | ||
|---|---|---|---|---|
| CAS Number | 439239-92-6 | Molecular Weight | 872.80900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C42H42F6N6O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Lasmiditan hemisuccinateLasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 μM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study. Lasmiditan showed efficacy in its primary endpoint, with a 2-hour placebo-subtracted headache response of 28.8%, though with frequent reports of dizziness, paresthesias, and vertigo. |
| Name | butanedioic acid,2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)pyridin-2-yl]benzamide |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C42H42F6N6O8 |
|---|---|
| Molecular Weight | 872.80900 |
| Exact Mass | 872.29700 |
| PSA | 206.18000 |
| LogP | 7.13100 |
| Lasmiditan succinate (USAN) |
| 2,4,6-Trifluoro-N-(6-((1-methylpiperidine-4-yl)carbonyl)pyridin-2-yl)benzamide hemisuccinate |
| UNII-W64YBJ346B |
| Lasmiditan succinate |
| Lasmiditan hemisuccinate |