Yoda 1

Modify Date: 2024-01-28 09:41:38

Yoda 1 Structure
Yoda 1 structure
Common Name Yoda 1
CAS Number 448947-81-7 Molecular Weight 355.265
Density 1.6±0.1 g/cm3 Boiling Point 538.4±60.0 °C at 760 mmHg
Molecular Formula C13H8Cl2N4S2 Melting Point N/A
MSDS N/A Flash Point 279.4±32.9 °C

 Use of Yoda 1


GlyT2-IN-1 is a glycine transporters GLYT2 inhibitor.Target: GLYT2The Glycine Transporter GlyT2 Controls the Dynamics of Synaptic Vesicle Refilling in Inhibitory Spinal Cord Neurons. GlyT2-IN-1 is a novel agonist of the mechanotransduction channel Piezo1, eliciting Ca2+ flux in Piezo1- but not vector-transfected cells.

 Names

Name GlyT2-IN-1
Synonym More Synonyms

 Yoda 1 Biological Activity

Description GlyT2-IN-1 is a glycine transporters GLYT2 inhibitor.Target: GLYT2The Glycine Transporter GlyT2 Controls the Dynamics of Synaptic Vesicle Refilling in Inhibitory Spinal Cord Neurons. GlyT2-IN-1 is a novel agonist of the mechanotransduction channel Piezo1, eliciting Ca2+ flux in Piezo1- but not vector-transfected cells.
Related Catalog
References

[1]. Rousseau F, et al. The glycine transporter GlyT2 controls the dynamics of synaptic vesicle refilling in inhibitory spinal cord neurons. J Neurosci. 2008 Sep 24;28(39):9755-9768.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 538.4±60.0 °C at 760 mmHg
Molecular Formula C13H8Cl2N4S2
Molecular Weight 355.265
Flash Point 279.4±32.9 °C
Exact Mass 353.956757
LogP 4.89
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.714

 Synonyms

2-{5-[(2,6-Dichlorobenzyl)sulfanyl]-1,3,4-thiadiazol-2-yl}pyrazine
2-[(2,6-dichlorobenzyl)thio]-5-pyrazin-2-yl-1,3,4-thiadiazole
MFCD00833175
Pyrazine, 2-[5-[[(2,6-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]-
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