Rehmannic acid

Modify Date: 2024-01-08 20:59:16

Rehmannic acid Structure
Rehmannic acid structure
Common Name Rehmannic acid
CAS Number 467-81-2 Molecular Weight 552.784
Density 1.1±0.1 g/cm3 Boiling Point 626.3±55.0 °C at 760 mmHg
Molecular Formula C35H52O5 Melting Point N/A
MSDS N/A Flash Point 187.9±25.0 °C

 Use of Rehmannic acid


Rehmannic acid (lantadene A) is a compound isolated from Lantana camara. Rehmannic acid shows considerable in vitro antioxidant, free radical scavenging capacity activities in a dose dependant manner. Rehmannic acid is a promising candidate for use as an antioxidant and hepatoprotective agent[1][2].

 Names

Name Rehmannic acid
Synonym More Synonyms

 Rehmannic acid Biological Activity

Description Rehmannic acid (lantadene A) is a compound isolated from Lantana camara. Rehmannic acid shows considerable in vitro antioxidant, free radical scavenging capacity activities in a dose dependant manner. Rehmannic acid is a promising candidate for use as an antioxidant and hepatoprotective agent[1][2].
Related Catalog
References

[1]. Barton, D. H. R., et al. Triterpenoids. Part XXIII. The nature of lantadene A.

[2]. Grace-Lynn C, et al. In vitro antioxidant activity potential of lantadene A, a pentacyclic triterpenoid of Lantana plants. Molecules. 2012;17(9):11185-11198.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 626.3±55.0 °C at 760 mmHg
Molecular Formula C35H52O5
Molecular Weight 552.784
Flash Point 187.9±25.0 °C
Exact Mass 552.381470
PSA 80.67000
LogP 9.56
Vapour Pressure 0.0±3.9 mmHg at 25°C
Index of Refraction 1.552

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RK0252000
CHEMICAL NAME :
Olean-12-en-28-oic acid, 22-beta-hydroxy-3-oxo-, 2-methylcrotonate, (Z)-
CAS REGISTRY NUMBER :
467-81-2
LAST UPDATED :
199012
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C35-H52-O5
MOLECULAR WEIGHT :
552.87
WISWESSER LINE NOTATION :
L F6 E6 B666 TV DUTJ A1 H1 H1 JOVY1&U2 KVQ N1 O1 S1 S1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
65 mg/kg
TOXIC EFFECTS :
Behavioral - food intake (animal) Gastrointestinal - decreased motility or constipation Liver - jaundice, other or unclassified
REFERENCE :
AUVJA2 Australian Veterinary Journal. (Australian Veterinary Assoc., Executive Director, 134-136 Hampden Road, Artarmon, N.S.W., Australia) V.2- 1927- Volume(issue)/page/year: 53,230,1977

 Safety Information

Hazard Codes Xi

 Synonyms

(22β)-22-{[(2Z)-2-Methyl-2-butenoyl]oxy}-3-oxoolean-12-en-28-oic acid
Olean-12-en-28-oic acid, 22-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]-3-oxo-, (22β)-