Trihexosylceramide (d18:1/12:0)

Modify Date: 2024-01-12 10:59:54

Trihexosylceramide (d18:1/12:0) structure	Common Name	Trihexosylceramide (d18:1/12:0)
	CAS Number	474943-80-1	Molecular Weight	806.08
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₂H₇₉NO₁₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Trihexosylceramide (d18:1/12:0)

Trihexosylceramide (d18:1/12:0) is a type of Trihexosylceramide. In the renal tissue of heterozygous Fabry's disease, the cytoplasm of glomerular epithelial cells appears foamy. Trihexosylceramide accumulated in glomerular epithelial cells as identified by immunostaining[1][2].

Name	N-[(E,2S,3R)-1-[(2R,5S)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,5R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3-hydroxyoctadec-4-en-2-yl]dodecanamide
Synonym	More Synonyms

Description	Trihexosylceramide (d18:1/12:0) is a type of Trihexosylceramide. In the renal tissue of heterozygous Fabry's disease, the cytoplasm of glomerular epithelial cells appears foamy. Trihexosylceramide accumulated in glomerular epithelial cells as identified by immunostaining[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Wang JR, et al. Improved sphingolipidomic approach based on ultra-high performance liquid chromatography and multiple mass spectrometries with application to cellular neurotoxicity. Anal Chem. 2014 Jun 17;86(12):5688-96. [2]. Fukushima M, et al. A female heterozygous patient with Fabry's disease with renal accumulation of trihexosylceramide detected with a monoclonal antibody. Am J Kidney Dis. 1995 Dec;26(6):952-5.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. Wang JR, et al. Improved sphingolipidomic approach based on ultra-high performance liquid chromatography and multiple mass spectrometries with application to cellular neurotoxicity. Anal Chem. 2014 Jun 17;86(12):5688-96.

[2]. Fukushima M, et al. A female heterozygous patient with Fabry's disease with renal accumulation of trihexosylceramide detected with a monoclonal antibody. Am J Kidney Dis. 1995 Dec;26(6):952-5.

Molecular Formula	C₄₂H₇₉NO₁₃
Molecular Weight	806.08
Exact Mass	805.55500
PSA	231.35000
LogP	4.49130
Storage condition	-20°C

D-lactosyl-ß-1,1' N-lauroyl-D-erythro-sphingosine

Trihexosylceramide (d18:1/12:0)

Use of Trihexosylceramide (d18:1/12:0)

Names

Trihexosylceramide (d18:1/12:0) Biological Activity

Chemical & Physical Properties

Synonyms