Pinocembrin-7-methyl ether

Modify Date: 2024-01-08 17:25:58

Pinocembrin-7-methyl ether structure	Common Name	Pinocembrin-7-methyl ether
	CAS Number	480-37-5	Molecular Weight	270.280
	Density	1.3±0.1 g/cm3	Boiling Point	494.9±45.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₄O₄	Melting Point	100ºC
	MSDS	Chinese USA	Flash Point	188.8±22.2 °C
	Symbol	GHS07	Signal Word	Warning

Use of Pinocembrin-7-methyl ether

Pinostrobin is a flavonoid can be found in many plants, and has anti-oxidant, anti-inflammatory, anti-cancer and neuroprotective properties. Pinostrobin is a potent PCSK9 inhibitor and inhibits the catalytic activity of PCSK9. Pinostrobin is a promising agent for cholesterol regulation and lipid management[1].

Name	pinostrobin
Synonym	More Synonyms

Description	Pinostrobin is a flavonoid can be found in many plants, and has anti-oxidant, anti-inflammatory, anti-cancer and neuroprotective properties. Pinostrobin is a potent PCSK9 inhibitor and inhibits the catalytic activity of PCSK9. Pinostrobin is a promising agent for cholesterol regulation and lipid management[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Inflammation/Immunology
Target	IC50: PCSK9[1]
References	[1]. Gao WY, et al. Pinostrobin Inhibits Proprotein Convertase Subtilisin/Kexin-type 9 (PCSK9) Gene Expression through the Modulation of FoxO3a Protein in HepG2 Cells.J Agric Food Chem. 2018 Jun 20;66(24):6083-6093.

Density	1.3±0.1 g/cm3
Boiling Point	494.9±45.0 °C at 760 mmHg
Melting Point	100ºC
Molecular Formula	C₁₆H₁₄O₄
Molecular Weight	270.280
Flash Point	188.8±22.2 °C
Exact Mass	270.089203
PSA	55.76000
LogP	4.11
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.612

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2932999099

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Dihydrotectochrysin

4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-, (S)-

Pinostrobin

2-Phenyl-5-hydroxy-7-methoxy-2,3-dihydro-4H-1-benzopyran-4-one

(S)-5-Hydroxy-7-methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one

Pistrobin

Pinocembrin-7-methyl ether

5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one

(2S)-5-Hydroxy-7-methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one

2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one

Pinostobin

4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-, (2S)-