Retronecine

Modify Date: 2024-01-12 12:58:17

Retronecine Structure
Retronecine structure
Common Name Retronecine
CAS Number 480-85-3 Molecular Weight 155.19400
Density 1.29g/cm3 Boiling Point 291.3ºC at 760mmHg
Molecular Formula C8H13NO2 Melting Point 119-120°
MSDS Chinese USA Flash Point 161.4ºC

 Use of Retronecine


Retronecine ((+)-Retronecine) is a pyrrolizidine alkaloid found in a variety of plants. Retronecine is the most common central core for other pyrrolizidine alkaloids[1].

 Names

Name (1R,7aR)-7-(Hydroxymethyl)-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-ol
Synonym More Synonyms

 Retronecine Biological Activity

Description Retronecine ((+)-Retronecine) is a pyrrolizidine alkaloid found in a variety of plants. Retronecine is the most common central core for other pyrrolizidine alkaloids[1].
Related Catalog
References

[1]. Joshua C. Smith, et al. Studies Towards the Total Synthesis of (+)- Retronecine and Anthracimycin. September 2016.

 Chemical & Physical Properties

Density 1.29g/cm3
Boiling Point 291.3ºC at 760mmHg
Melting Point 119-120°
Molecular Formula C8H13NO2
Molecular Weight 155.19400
Flash Point 161.4ºC
Exact Mass 155.09500
PSA 43.70000
Vapour Pressure 0.000211mmHg at 25°C
Index of Refraction 1.611

 Safety Information

RIDADR UN 1544
RTECS VH7175000
Packaging Group III
Hazard Class 6.1(b)

 Articles26

More Articles
Diversity of pyrrolizidine alkaloids in native and invasive Senecio pterophorus (Asteraceae): implications for toxicity.

Phytochemistry 108 , 137-46, (2014)

Changes in plant chemical defenses after invasion could have consequences on the invaded ecosystems by modifying the interactions between plants and herbivores and facilitating invasion success. Howev...

Transfer of [3H]pyrrolizidine alkaloids from Senecio vulgaris L. and metabolites into rat milk and tissues.

Toxicol. Lett. 17(3-4) , 283-8, (1983)

[3H]Retronecine and [3H]necic acid-labelled senecionine and seneciphylline were prepared biosynthetically with seedlings of Senecio vulgaris L. using [2,3-3H]putrescine and [4,5-3H]isoleucine, respect...

In vivo covalent binding of retronecine-labelled [3H]seneciphylline and [3H]senecionine to DNA of rat liver, lung and kidney.

Chem. Biol. Interact. 54(1) , 57-69, (1985)

Retronecine-labelled [3H]seneciphylline ([3H]SPH) and [3H]senecionine ([3H]SON) of high specific radioactivity (22 and 49 mCi/mmol, respectively) were prepared biosynthetically with seedlings of Senec...

 Synonyms

(1R,7aR)-7-hydroxymethyl-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-ol
Hopeaphenol
(1R-trans)-2,3,5,7a-Tetrahydro-1-hydroxy-1H-pyrrolizine-7-methanol
Retronecine
(1R,6S,7R,11bR)-1-(3,4-dihydroxyphenyl)-1,6,7,11b-tetrahydro-6-[(1R,6S,7R,11bR)-1,6,7,11b-tetrahydro-4,8,10-trihydroxy-1,7-bis(4-hydroxyphenyl)benzo[6,7]cyclohepta[1,2,3-cd]benzofuran-6-yl]-7-(4-hydroxyphenyl)benzo[6,7]cyclohepta[1,2,3-cd]benzofuran-4,8,10-triol
(7aR)-7-Hydroxymethyl-(7ar)-2,3,5,7a-tetrahydro-1H-pyrrolizin-1t-ol
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