Toddalolactone
Modify Date: 2024-01-02 10:10:31
Toddalolactone structure
|
Common Name | Toddalolactone | ||
|---|---|---|---|---|
| CAS Number | 483-90-9 | Molecular Weight | 308.326 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 530.0±50.0 °C at 760 mmHg | |
| Molecular Formula | C16H20O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 195.5±23.6 °C | |
Use of ToddalolactoneToddalolactone, a main component of Toddalia asiatica, inhibits the activity of recombinant human plasminogen activator inhibitor-1 (PAI-1), with an IC50 value of 37.31 μM[1]. |
| Name | 6-[(2R)-2,3-dihydroxy-3-methylbutyl]-5,7-dimethoxychromen-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | Toddalolactone, a main component of Toddalia asiatica, inhibits the activity of recombinant human plasminogen activator inhibitor-1 (PAI-1), with an IC50 value of 37.31 μM[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Toddalolactone, a natural coumarin, inhibits PAI-1 activity by preventing the formation of a stable PAI-1/uPA covalent complex, suggesting that the inhibitory effect of Toddalolactone may be due to the interference of close contact between plasminogen activator and the active center of PAI-1[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 530.0±50.0 °C at 760 mmHg |
| Molecular Formula | C16H20O6 |
| Molecular Weight | 308.326 |
| Flash Point | 195.5±23.6 °C |
| Exact Mass | 308.125977 |
| PSA | 89.13000 |
| LogP | 0.88 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.569 |
| Storage condition | 2-8C |
|
~15%
Toddalolactone CAS#:483-90-9 |
| Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 13 p. 1681 - 1684 |
![2H-1-Benzopyran-2-one, 6-[(2R)-2-hydroxy-3-methyl-3-buten-1-yl]-5,7-dimethoxy structure](https://image.chemsrc.com/caspic/419/137764-14-8.png)
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| 2H-1-Benzopyran-2-one, 6-(2,3-dihydroxy-3-methylbutyl)-5,7-dimethoxy- |
| 6-[(2r)-2,3-dihydroxy-3-methylbutyl]-5,7-dimethoxy-2h-chromen-2-one |
| 6-(2,3-Dihydroxy-3-methylbutyl)-5,7-dimethoxy-2H-chromen-2-one |
| (+)-toddalolactone |
| Toddaline |
| Toddalolactone |
- Shanghai Nianxing Industrial Co., Ltd
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- China
- Product Name: toddalolactone
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- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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Price: ￥1190/5 mg
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