DPH structure
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Common Name | DPH | ||
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CAS Number | 484049-04-9 | Molecular Weight | 336.32000 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C18H13FN4O2 | Melting Point | N/A | |
MSDS | USA | Flash Point | N/A |
Use of DPHDPH is a potent cell permeable c-Abl activator, which displays potent enzymatic and cellular activity in stimulating c-Abl activation. |
Name | 5-[3-(4-fluorophenyl)-1-phenylpyrazol-4-yl]imidazolidine-2,4-dione |
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Synonym | More Synonyms |
Description | DPH is a potent cell permeable c-Abl activator, which displays potent enzymatic and cellular activity in stimulating c-Abl activation. |
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Related Catalog | |
In Vitro | DPH binds to the myristoyl binding site and prevents the formation of the bent conformation of the αI helix through steric hindrance, a mode of action distinct from the previously identified allosteric c-Abl inhibitor, GNF-2, that also binds to the myristoyl binding site. DPH represents the first cell-permeable, small-molecule tool compound for c-Abl activation[1]. |
References |
Molecular Formula | C18H13FN4O2 |
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Molecular Weight | 336.32000 |
Exact Mass | 336.10200 |
PSA | 83.00000 |
LogP | 2.47480 |
Storage condition | 2-8℃ |
RIDADR | NONH for all modes of transport |
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5-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]imidazolidine-2,4-dione |
HMS2301N21 |
5-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]-2,4-imidazolidinedione |
DPH |