9-Fluorenone

Modify Date: 2024-01-02 12:37:05

9-Fluorenone Structure
9-Fluorenone structure
Common Name 9-Fluorenone
CAS Number 486-25-9 Molecular Weight 180.20
Density 1.2±0.1 g/cm3 Boiling Point 341.5±0.0 °C at 760 mmHg
Molecular Formula C13H8O Melting Point 80-83 °C(lit.)
MSDS USA Flash Point 144.1±13.7 °C

 Use of 9-Fluorenone


9H-fluoren-9-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name fluoren-9-one
Synonym More Synonyms

 9-Fluorenone Biological Activity

Description 9H-fluoren-9-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro 用作有机合成中间体。

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 341.5±0.0 °C at 760 mmHg
Melting Point 80-83 °C(lit.)
Molecular Formula C13H8O
Molecular Weight 180.20
Flash Point 144.1±13.7 °C
Exact Mass 180.057510
PSA 17.07000
LogP 3.58
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.667
Storage condition Store at RT.
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility insoluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LL8925000
CHEMICAL NAME :
9H-Fluoren-9-one
CAS REGISTRY NUMBER :
486-25-9
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C13-H8-O
MOLECULAR WEIGHT :
180.21
WISWESSER LINE NOTATION :
L B656 HVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 23,325,1989 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
300 mg/kg/26W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 7,453,1947 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - Z0225 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 28 (estimated)

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS LL8925000
Packaging Group II; III
Hazard Class 4.1
HS Code 2914399090

 Customs

HS Code 2914399090
Summary 2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

 Articles28

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Rational design of indoleamine 2,3-dioxygenase inhibitors.

J. Med. Chem. 53 , 1172-89, (2010)

Indoleamine 2,3-dioxygenase (IDO) is an important therapeutic target for the treatment of diseases such as cancer that involve pathological immune escape. We have used the evolutionary docking algorit...

Photosensitizing properties of compounds related to benzophenone.

Acta Derm. Venereol. 93(1) , 30-2, (2013)

Benzophenone is a phototoxic compound with absorption maxima in the ultraviolet A (UVA) and ultraviolet B (UVB) range. Many benzophenone derivatives are known to be photosensitizing. On the other hand...

Broad spectrum analysis of polar and apolar organic compounds in submicron atmospheric particles.

J. Chromatogr. A. 1404 , 28-38, (2015)

A method for the quantitative analysis of organic compounds on submicron particulate matter (PM1) collected on quartz filters was developed. The compounds analyzed encompassed C22-C35 alkanes, polycyc...

 Synonyms

9-Fluorenone
Diphenylene ketone
MFCD00001141
9H-Fluoren-9-one
EINECS 207-630-7
fluoren-9-one
Fluorenone
9-Oxofluorene
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