savinin

Modify Date: 2024-01-11 05:43:07

savinin structure	Common Name	savinin
	CAS Number	493-95-8	Molecular Weight	352.34
	Density	1.4±0.1 g/cm3	Boiling Point	573.5±39.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₁₆O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	254.5±27.1 °C

Use of savinin

Savinin is a lignan, whicn can serves as a valuable pharmacophore to exhibit anti-inflammatory effect[1][2].

Name	(3E,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-(1,3-benzodioxol-5-ylmethylidene)oxolan-2-one
Synonym	More Synonyms

Description	Savinin is a lignan, whicn can serves as a valuable pharmacophore to exhibit anti-inflammatory effect[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Jung HJ, et al. Anticholinesterase and β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitory Compounds from the Heartwood of Juniperus chinensis. Chem Pharm Bull (Tokyo). 2015;63(11):955-60. [2]. Cho JY, et al. Savinin, a lignan from Pterocarpus santalinus inhibits tumor necrosis factor-alpha production and T cell proliferation. Biol Pharm Bull. 2001 Feb;24(2):167-71.

Description

Savinin is a lignan, whicn can serves as a valuable pharmacophore to exhibit anti-inflammatory effect[1][2].

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. Jung HJ, et al. Anticholinesterase and β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitory Compounds from the Heartwood of Juniperus chinensis. Chem Pharm Bull (Tokyo). 2015;63(11):955-60.

[2]. Cho JY, et al. Savinin, a lignan from Pterocarpus santalinus inhibits tumor necrosis factor-alpha production and T cell proliferation. Biol Pharm Bull. 2001 Feb;24(2):167-71.

Density	1.4±0.1 g/cm3
Boiling Point	573.5±39.0 °C at 760 mmHg
Molecular Formula	C₂₀H₁₆O₆
Molecular Weight	352.34
Flash Point	254.5±27.1 °C
Exact Mass	352.094696
PSA	63.22000
LogP	3.83
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.679

Hazard Codes	Xi

(-)-isohibalactone

CAS#:22554-63-8

~79%

savinin

CAS#:493-95-8

Literature: Honda, Toshio; Kimura, Nobuaki; Sato, Shigeki; Kato, Daishiro; Tominaga, Hideo Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 8 p. 1043 - 1046

(2E)-3-(1,3-Ben...

CAS#:2373-80-0

savinin

CAS#:493-95-8

Literature: Charlton, James L.; Chee, Gaik-Lean Canadian Journal of Chemistry, 1997 , vol. 75, # 8 p. 1076 - 1083

3-(3,4-Methylen...

CAS#:2815-95-4

savinin

CAS#:493-95-8

Literature: Charlton, James L.; Chee, Gaik-Lean Canadian Journal of Chemistry, 1997 , vol. 75, # 8 p. 1076 - 1083

(4R)-4-(1,3-ben...

CAS#:17187-77-8

savinin

CAS#:493-95-8

Literature: Charlton, James L.; Chee, Gaik-Lean Canadian Journal of Chemistry, 1997 , vol. 75, # 8 p. 1076 - 1083

(4S)-4-isopropy...

CAS#:161745-67-1

savinin

CAS#:493-95-8

Literature: Charlton, James L.; Chee, Gaik-Lean Canadian Journal of Chemistry, 1997 , vol. 75, # 8 p. 1076 - 1083

(R)-tert-butyl ...

CAS#:196804-99-6

savinin

CAS#:493-95-8

Literature: Charlton, James L.; Chee, Gaik-Lean Canadian Journal of Chemistry, 1997 , vol. 75, # 8 p. 1076 - 1083

Precursor 6
CAS#:22554-63-8 (-)-isohibalactone CAS#:2373-80-0 (2E)-3-(1,3-Ben... CAS#:2815-95-4 3-(3,4-Methylen... CAS#:17187-77-8 (4R)-4-(1,3-ben...
CAS#:161745-67-1 (4S)-4-isopropy... CAS#:196804-99-6 (R)-tert-butyl ...
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