UNII:LK024V9U3C

Modify Date: 2024-01-03 16:59:20

UNII:LK024V9U3C Structure
UNII:LK024V9U3C structure
Common Name UNII:LK024V9U3C
CAS Number 494-90-6 Molecular Weight 150.218
Density 1.0±0.1 g/cm3 Boiling Point 210.7±9.0 °C at 760 mmHg
Molecular Formula C10H14O Melting Point N/A
MSDS Chinese USA Flash Point 75.6±0.0 °C

 Use of UNII:LK024V9U3C


Menthofuran is a proximate toxic metabolite of (R)-(+)-Pulegone. Menthofuran regulates essential oil biosynthesis in peppermint by controlling a downstream monoterpene reductase[1][2].

 Names

Name menthofuran
Synonym More Synonyms

 UNII:LK024V9U3C Biological Activity

Description Menthofuran is a proximate toxic metabolite of (R)-(+)-Pulegone. Menthofuran regulates essential oil biosynthesis in peppermint by controlling a downstream monoterpene reductase[1][2].
Related Catalog
References

[1]. Gordon WP, et al. The metabolism of the abortifacient terpene, (R)-(+)-pulegone, to a proximate toxin, menthofuran. Drug Metab Dispos. 1987 Sep-Oct;15(5):589-94.

[2]. Mahmoud SS, et al. Menthofuran regulates essential oil biosynthesis in peppermint by controlling a downstream monoterpene reductase. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14481-6.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 210.7±9.0 °C at 760 mmHg
Molecular Formula C10H14O
Molecular Weight 150.218
Flash Point 75.6±0.0 °C
Exact Mass 150.104462
PSA 13.14000
LogP 4.02
Vapour Pressure 0.3±0.4 mmHg at 25°C
Index of Refraction 1.490
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS DF7995750

 Articles26

More Articles
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.

Curr. Drug Metab. 6 , 413-54, (2005)

The inhibition of human cytochrome P450s (CYPs) is one of the most common mechanisms which can lead to drug-drug interactions. The inhibition of CYPs can be reversible (competitive or non-competitive)...

In vitro production of M. × piperita not containing pulegone and menthofuran.

Acta Biochim. Pol. 59(3) , 417-23, (2012)

The essential oils (EOs) and static headspaces (HSs) of in vitro plantlets and callus of Mentha x piperita were characterized by GC-MS analysis. Leaves were used as explants to induce in vitro plant m...

Volatile organic compounds from rhizobacteria increase biosynthesis of essential oils and growth parameters in peppermint (Mentha piperita).

Plant Physiol. Biochem. 49(10) , 1177-82, (2011)

Volatile organic compounds (VOCs), characterized by low molecular weight and high vapor pressure, are produced by all organisms as part of normal metabolism, and play important roles in communication ...

 Synonyms

3,9-Epoxy-p-mentha-3,8-diene
3,6-dimethyl-4,5,6,7-tetrahydrobenzo[b]furan
MENTHOFURAN(SG)
FEMA 3235
EINECS 207-795-5
Menthofurane
4,5,6,7-Tetrahydro-3,6-dimethyl-1-benzofuran
MENTHOFURAN
UNII:LK024V9U3C
Menthofuran 10GR
3,6-dimethyl-4,5,6,7-tetrahydro-benzofuran
Benzofuran, 4,5,6,7-tetrahydro-3,6-dimethyl-
p-Mentha-3,8-diene,3,9-epoxy
MENTHOFURAN,NATURAL
MENTHOFURAN WITH GC
MFCD00041851
3,6-Dimethyl-4,5,6,7-tetrahydro-1-benzofuran
2-4,5,6,7-tetrahydro-3,6-dimethylbenzofuran
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