Cyclo(-RGDfK) TFA

Modify Date: 2024-04-02 11:28:07

Cyclo(-RGDfK) TFA structure	Common Name	Cyclo(-RGDfK) TFA
	CAS Number	500577-51-5	Molecular Weight	717.694
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₄₂F₃N₉O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cyclo(-RGDfK) TFA

Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM[1]. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface[3].

Name	Cyclo (-RGDfK) 2,2,2-Trifluoroacetic acid
Synonym	More Synonyms

Description	Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM[1]. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface[3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cytoskeleton >> Integrin
Target	IC50: 0.94 nM (αvβ3 integrin)[1]
In Vitro	Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin and exhibits a IC50 of 0.94 nM[1]. [66Ga]DOTA-E-[c(RGDfK)]2 can be prepared with high radiochemical purity (>97%), specific activity (36-67GBq/μM), in vitro stability, and moderate protein binding. MicroPET imaging up to 24 post-injection showed contrasting tumors reflecting αvβ3-targeted tracer accumulation[2].
References	[1]. Simecek J, et al. Benefits of NOPO as chelator in gallium-68 peptides, exemplified by preclinical characterization of (68)Ga-NOPO-c(RGDfK). Mol Pharm. 2014 May 5;11(5):1687-95. [2]. Lopez-Rodriguez V, et al. Preparation and preclinical evaluation of (66)Ga-DOTA-E(c(RGDfK))2 as a potential theranostic radiopharmaceutical. Nucl Med Biol. 2015 Feb;42(2):109-14. [3]. V Lopez-Rodriguez, et al. Preparation and preclinical evaluation of (66)Ga-DOTA-E(c(RGDfK))2 as a potential theranostic radiopharmaceutical. Nucl Med Biol. 2015 Feb;42(2):109-14.

Molecular Formula	C₂₉H₄₂F₃N₉O₉
Molecular Weight	717.694
Exact Mass	717.305786

Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-lysyl) trifluoroacetate (1:1)

Acetic acid, 2,2,2-trifluoro-, compd. with cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-lysyl) (1:1)

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Cyclo(-RGDfK) TFA
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Cyclo(-RGDfK) TFA
Price: ￥986.0/5mg ￥1676.0/10mg ￥3926.0/50mg ￥396.0/1mg
Purity: 98.0%
Delivery: 1 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Cyclo(-RGDfK) TFA
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Get all suppliers and price by the below link:

Cyclo(-RGDfK) TFA suppliers

Price: ￥2190/10 mM * 1 mL in DMSO

Reference only. check more Cyclo(-RGDfK) TFA price

Cyclo(-RGDfK) TFA

Use of Cyclo(-RGDfK) TFA

Names

Cyclo(-RGDfK) TFA Biological Activity

Chemical & Physical Properties

Synonyms