Dasolampanel [USAN:INN]

Modify Date: 2024-08-24 09:30:25

Dasolampanel [USAN:INN] Structure
Dasolampanel [USAN:INN] structure
Common Name Dasolampanel [USAN:INN]
CAS Number 503294-13-1 Molecular Weight 377.825
Density 1.4±0.1 g/cm3 Boiling Point 642.2±65.0 °C at 760 mmHg
Molecular Formula C17H20ClN5O3 Melting Point N/A
MSDS N/A Flash Point 342.2±34.3 °C

 Use of Dasolampanel [USAN:INN]


Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine. Migraine Discontinued

 Names

Name Dasolampanel
Synonym More Synonyms

 Dasolampanel [USAN:INN] Biological Activity

Description Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine. Migraine Discontinued
References References 1. Wallace MS, et al. Pain Med. 2012 Dec;13(12):1601-10. 2. Martinez-Perez JA, et al. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6463-6. View Related Products by Target iGluR Migraine

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 642.2±65.0 °C at 760 mmHg
Molecular Formula C17H20ClN5O3
Molecular Weight 377.825
Flash Point 342.2±34.3 °C
Exact Mass 377.125458
LogP 1.99
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.605

 Synonyms

Dasolampanel
3-Isoquinolinecarboxylic acid, 6-[3-chloro-2-(1H-tetrazol-5-yl)phenoxy]decahydro-, (3S,4aS,6S,8aR)-
(3S,4aS,6S,8aR)-6-[3-Chloro-2-(1H-tetrazol-5-yl)phenoxy]decahydro-3-isoquinolinecarboxylic acid
1P85D6BE9K
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