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503294-13-1

503294-13-1 structure
503294-13-1 structure
  • Name: Dasolampanel [USAN:INN]
  • Chemical Name: Dasolampanel
  • CAS Number: 503294-13-1
  • Molecular Formula: C17H20ClN5O3
  • Molecular Weight: 377.825
  • Create Date: 2020-01-11 18:02:40
  • Modify Date: 2024-08-24 09:30:25
  • Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine. Migraine Discontinued

Name Dasolampanel
Synonyms Dasolampanel
3-Isoquinolinecarboxylic acid, 6-[3-chloro-2-(1H-tetrazol-5-yl)phenoxy]decahydro-, (3S,4aS,6S,8aR)-
(3S,4aS,6S,8aR)-6-[3-Chloro-2-(1H-tetrazol-5-yl)phenoxy]decahydro-3-isoquinolinecarboxylic acid
1P85D6BE9K
Description Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine. Migraine Discontinued
References References 1. Wallace MS, et al. Pain Med. 2012 Dec;13(12):1601-10. 2. Martinez-Perez JA, et al. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6463-6. View Related Products by Target iGluR Migraine
Density 1.4±0.1 g/cm3
Boiling Point 642.2±65.0 °C at 760 mmHg
Molecular Formula C17H20ClN5O3
Molecular Weight 377.825
Flash Point 342.2±34.3 °C
Exact Mass 377.125458
LogP 1.99
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.605