Docosanedioic acid structure
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Common Name | Docosanedioic acid | ||
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CAS Number | 505-56-6 | Molecular Weight | 370.566 | |
Density | 1.0±0.1 g/cm3 | Boiling Point | 527.0±23.0 °C at 760 mmHg | |
Molecular Formula | C22H42O4 | Melting Point | 72-80 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 286.6±19.1 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of Docosanedioic acidDocosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2]. |
Name | docosanedioic acid |
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Synonym | More Synonyms |
Description | Docosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2]. |
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Related Catalog | |
Target |
Non-cleavable |
In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 527.0±23.0 °C at 760 mmHg |
Melting Point | 72-80 °C(lit.) |
Molecular Formula | C22H42O4 |
Molecular Weight | 370.566 |
Flash Point | 286.6±19.1 °C |
Exact Mass | 370.308319 |
PSA | 74.60000 |
LogP | 8.24 |
Vapour Pressure | 0.0±3.0 mmHg at 25°C |
Index of Refraction | 1.474 |
Storage condition | 2-8°C |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36 |
RIDADR | UN 1824 |
WGK Germany | 3 |
HS Code | 2917190090 |
Precursor 10 | |
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DownStream 6 | |
HS Code | 2917190090 |
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Summary | 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
1,22-Docosanedioic acid |
1,20-Eicosanedicarboxylic acid |
Phellogenic acid |
docosanedicarboxylic acid |
MFCD00002807 |
docosandioic acid |
EINECS 204-010-8 |
Phelogenic acid |
Docosanedioic acid |
1,22-Docosanedoic acid |
Docosandisaeure |
Felogenic acid |