CP-9
Modify Date: 2024-01-09 10:31:52
CP-9 structure
|
Common Name | CP-9 | ||
|---|---|---|---|---|
| CAS Number | 505056-50-8 | Molecular Weight | 400.399 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 599.6±50.0 °C at 760 mmHg | |
| Molecular Formula | C15H11F3N4O2S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 316.5±30.1 °C | |
Use of CP-9A potent Hsp90α/p23 interaction inhibitor with IC50 of 3.2 uM; 5-fold less potent for Hsp90β/p23 interaction (IC50=15.3 uM); leads to various levels of degradation of pAkt/total Akt and Raf-1 in cancer cell lines, but has no effect on the expression of the Hsp90 client proteins in normal mouse embryonic fibroblasts (MEFs); inhibits cell proliferation, glucose metabolism, and mammalian thymidine kinase activities in multiple cancer cell lines. |
| Name | N-(5-Methyl-1,2-oxazol-3-yl)-2-{[4-(2-thienyl)-6-(trifluoromethyl)-2-pyrimidinyl]sulfanyl}acetamide |
|---|---|
| Synonym | More Synonyms |
| Description | A potent Hsp90α/p23 interaction inhibitor with IC50 of 3.2 uM; 5-fold less potent for Hsp90β/p23 interaction (IC50=15.3 uM); leads to various levels of degradation of pAkt/total Akt and Raf-1 in cancer cell lines, but has no effect on the expression of the Hsp90 client proteins in normal mouse embryonic fibroblasts (MEFs); inhibits cell proliferation, glucose metabolism, and mammalian thymidine kinase activities in multiple cancer cell lines. |
|---|---|
| References | References 1. Chan CT, et al. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):E2476-85. View Related Products by Target Heat Shock Protein (HSP) |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 599.6±50.0 °C at 760 mmHg |
| Molecular Formula | C15H11F3N4O2S2 |
| Molecular Weight | 400.399 |
| Flash Point | 316.5±30.1 °C |
| Exact Mass | 400.027557 |
| LogP | 3.42 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.618 |
| N-(5-Methyl-1,2-oxazol-3-yl)-2-{[4-(2-thienyl)-6-(trifluoromethyl)-2-pyrimidinyl]sulfanyl}acetamide |
| N-(5-Methyl-1,2-oxazol-3-yl)-2-{[4-(2-thienyl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl}acetamide |
| Acetamide, N-(5-methyl-3-isoxazolyl)-2-[[4-(2-thienyl)-6-(trifluoromethyl)-2-pyrimidinyl]thio]- |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: CP-9
- Price: ￥Inquiry/25mg ￥Inquiry/100mg ￥Inquiry/500mg
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: CP-9
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: CP-9
- Price: $Inquiry/25mg $Inquiry/100mg $Inquiry/500mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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