Rotundifuran

Modify Date: 2024-01-21 00:29:40

Rotundifuran Structure
Rotundifuran structure
Common Name Rotundifuran
CAS Number 50656-65-0 Molecular Weight 362.50300
Density N/A Boiling Point N/A
Molecular Formula C22H34O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Rotundifuran


Rotundifuran, a labdane type diterpene, is isolated from Vitex rotundifolia. Rotundifuran can inhibit the cell cycle progression and induce apoptosis in human myeloid leukaemia cells[1][2].

 Names

Name [(1R,3R,4R,4aS,8aS)-4-[2-(furan-3-yl)ethyl]-4-hydroxy-3,4a,8,8-tetramethyl-2,3,5,6,7,8a-hexahydro-1H-naphthalen-1-yl] acetate
Synonym More Synonyms

 Rotundifuran Biological Activity

Description Rotundifuran, a labdane type diterpene, is isolated from Vitex rotundifolia. Rotundifuran can inhibit the cell cycle progression and induce apoptosis in human myeloid leukaemia cells[1][2].
Related Catalog
References

[1]. Ko WG, et, al. Rotundifuran, a labdane type diterpene from Vitex rotundifolia, induces apoptosis in human myeloid leukaemia cells. Phytother Res. 2001 Sep; 15(6):535-7.

[2]. Li WX, et, al. Labdane-type diterpenes as new cell cycle inhibitors and apoptosis inducers from Vitex trifolia L. J Asian Nat Prod Res. 2005 Apr; 7(2): 95-105.

 Chemical & Physical Properties

Molecular Formula C22H34O4
Molecular Weight 362.50300
Exact Mass 362.24600
PSA 59.67000
LogP 4.74740
Storage condition 2-8℃

 Synonyms

Rotundifuran
UNII-T2UY9AYG4O
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