Cenderitide

Modify Date: 2024-01-22 17:17:22

Cenderitide structure	Common Name	Cenderitide
	CAS Number	507289-11-4	Molecular Weight	3745.27
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅₈H₂₆₃N₄₉O₅₀S₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cenderitide

Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research[1][2][3].

Name	Cenderitide

Description	Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research[1][2][3].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Guanylate Cyclase
In Vitro	Cenderitide has antiproliferative, anti-fibrotic, and anti-hypertrophic properties[1].
In Vivo	In vivo in normal canines, Cenderitide (10, 50, and 100 ng/kg) is a potent cGMP stimulator that has renal enhancing and cardiac unloading effects, with less reduction of blood pressure[1][4].

Molecular Formula	C₁₅₈H₂₆₃N₄₉O₅₀S₃
Molecular Weight	3745.27

Cenderitide

Use of Cenderitide

Names

Cenderitide Biological Activity

Chemical & Physical Properties