Vasicinol

Modify Date: 2024-01-10 17:20:38

Vasicinol Structure
Vasicinol structure
Common Name Vasicinol
CAS Number 5081-51-6 Molecular Weight 204.23
Density 1.5±0.1 g/cm3 Boiling Point 465.0±55.0 °C at 760 mmHg
Molecular Formula C11H12N2O2 Melting Point N/A
MSDS N/A Flash Point 235.1±31.5 °C

 Use of Vasicinol


Vasicinol is a reversible inhibitor of sucrase (IC50: 250 μM). Vasicinol is a HbF inducer. Vasicinol also inhibits Angiotensin-converting Enzyme (ACE). Vasicinol is apyrroquinazoline alkaloid that can be isolated from Adhatoda vasica[1][2].

 Names

Name Vasicinol
Synonym More Synonyms

 Vasicinol Biological Activity

Description Vasicinol is a reversible inhibitor of sucrase (IC50: 250 μM). Vasicinol is a HbF inducer. Vasicinol also inhibits Angiotensin-converting Enzyme (ACE). Vasicinol is apyrroquinazoline alkaloid that can be isolated from Adhatoda vasica[1][2].
Related Catalog
References

[1]. Gao H, et al. Inhibitory effect on α-glucosidase by Adhatoda vasica Nees. Food Chem. 2008 Jun 1;108(3):965-72.  

[2]. Tehreem S, et al. A UPLC-DAD-Based Bio-Screening Assay for the Evaluation of the Angiotensin Converting Enzyme Inhibitory Potential of Plant Extracts and Compounds: Pyrroquinazoline Alkaloids from Adhatoda vasica as a Case Study. Molecules. 2021 Nov 18;26(22):6971.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 465.0±55.0 °C at 760 mmHg
Molecular Formula C11H12N2O2
Molecular Weight 204.23
Flash Point 235.1±31.5 °C
Exact Mass 204.089874
PSA 56.06000
LogP -1.73
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.743

 Safety Information

Hazard Codes Xi

 Synonyms

(3R)-1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazoline-3,7-diol
Pyrrolo[2,1-b]quinazoline-3,7-diol, 1,2,3,9-tetrahydro-, (3S)-
Pyrrolo[2,1-b]quinazoline-3,7-diol, 1,2,3,9-tetrahydro-, (3R)-
Pyrrolo(2,1-b)quinazoline-3,7-diol, 1,2,3,9-tetrahydro-, (R)-
(3S)-1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazoline-3,7-diol
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