metolachlor [ANSI, WSSA]

Modify Date: 2024-01-02 11:07:12

metolachlor [ANSI, WSSA] structure	Common Name	metolachlor [ANSI, WSSA]
	CAS Number	51218-45-2	Molecular Weight	283.794
	Density	1.1±0.1 g/cm3	Boiling Point	406.8±45.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₂₂ClNO₂	Melting Point	-62.1 °C
	MSDS	Chinese USA	Flash Point	199.8±28.7 °C
	Symbol	GHS07	Signal Word	Warning

Use of metolachlor [ANSI, WSSA]

Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers[1][2].

Name	metolachlor
Synonym	More Synonyms

Description	Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Jingqian Xie, et al. Metolachlor Stereoisomers: Enantioseparation, Identification and Chiral Stability. J Chromatogr A. 2016 Sep 9;1463:42-8. [2]. D M Stamper, et al. Biodegradation of the Acetanilide Herbicides Alachlor, Metolachlor, and Propachlor. Crit Rev Microbiol. 1998;24(1):1-22.

Description

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Jingqian Xie, et al. Metolachlor Stereoisomers: Enantioseparation, Identification and Chiral Stability. J Chromatogr A. 2016 Sep 9;1463:42-8.

[2]. D M Stamper, et al. Biodegradation of the Acetanilide Herbicides Alachlor, Metolachlor, and Propachlor. Crit Rev Microbiol. 1998;24(1):1-22.

Density	1.1±0.1 g/cm3
Boiling Point	406.8±45.0 °C at 760 mmHg
Melting Point	-62.1 °C
Molecular Formula	C₁₅H₂₂ClNO₂
Molecular Weight	283.794
Flash Point	199.8±28.7 °C
Exact Mass	283.133911
PSA	29.54000
LogP	3.00
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.533

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AN3430000

CHEMICAL NAME :: o-Acetotoluidide, 2-chloro-6'-ethyl-N-(2-methoxy-1-methylethyl)-

CAS REGISTRY NUMBER :: 51218-45-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 23

MOLECULAR FORMULA :: C15-H22-Cl-N-O2

MOLECULAR WEIGHT :: 283.83

WISWESSER LINE NOTATION :: 2R C1 BNV1GY1&1O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1750 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3170 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 620 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >9 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3170 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 410 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: >2510 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5460 mg/kg/13W-C

TOXIC EFFECTS :: Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 131 gm/kg/2Y-C

TOXIC EFFECTS :: Liver - other changes Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 263 gm/kg/2Y-C

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 4550 mg/kg/26W-C

TOXIC EFFECTS :: Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 10 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 100 ug/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 281,295,1992 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H317
Precautionary Statements	P280
Personal Protective Equipment	Eyeshields;Faceshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R43
Safety Phrases	S36/37
RIDADR	UN1648 3/PG 2
RTECS	AN3430000
HS Code	2924299017

2-ethyl-N-(2-me...

CAS#:51219-00-2

Chloroacetyl ch...

CAS#:79-04-9

metolachlor [AN...

CAS#:51218-45-2

Literature: Ciba-Geigy Corporation Patent: US4317916 A1, 1982 ;

2-Ethyl-6-methy...

CAS#:24549-06-2

metolachlor [AN...

CAS#:51218-45-2

Literature: Ciba-Geigy Patent: CH581607 , 1976 ; Chem.Abstr., 1977 , vol. 86, # 72242

Precursor 3
CAS#:51219-00-2 2-ethyl-N-(2-me... CAS#:79-04-9 Chloroacetyl ch... CAS#:24549-06-2 2-Ethyl-6-methy...
DownStream 1
CAS#:65513-61-3 2-chloro-N-(2-e...

HS Code	2924299017
Summary	2924299017 2-chloro-n-(2-ethyl-6-methylphenyl)-n-(1-methoxypropan-2-yl)acetamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

Embryotoxic and genotoxic effects of heavy metals and pesticides on early life stages of Pacific oyster (Crassostrea gigas).

Mar. Pollut. Bull. 64(12) , 2663-70, (2012)

This study evaluated embryotoxicity and genotoxicity of two dissolved metals copper and cadmium (Cu and Cd) and two pesticides (metolachlor and irgarol) occurring in Arcachon Bay (SW France) in Pacifi...

Polar organic chemical integrative samplers for pesticides monitoring: impacts of field exposure conditions.

Sci. Total Environ. 488-489 , 188-96, (2014)

This study focuses on how Polar Organic Chemical Integrative Samplers (POCIS) work in real environmental conditions. A selection of 23 polar pesticides and 8 metabolites were investigated by exposure ...

Biodegradation of the acetanilide herbicides alachlor, metolachlor, and propachlor.

Crit. Rev. Microbiol 24(1) , 1-22, (1998)

Alachlor, metolachlor, and propachlor are detoxified in biological systems by the formation of glutathione-acetanilide conjugates. This conjugation is mediated by glutathione-S-transferase, which is p...

2-Chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl)acetamide

Cotoran multi

2-Chloro-6'-ethyl-N-(2-methoxy-1-methylethyl)acet-o-toluidide

2R C1 BNV1GY1&1O1

2-chloro-N-(6-ethyl-o-tolyl)-N-[(1RS)-2-methoxy-1-methylethyl]acetamide

Primagram

2-chloro-6’-ethyl-N-[(1RS)-2-methoxy-1-methylethyl]acet-o-toluidide

Metolachlor

Bicep

Primextra

EINECS 257-060-8

Acetamide, 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl)-

2-Chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)acetamide

2-Chloro-N-(2-ethyl-6-methylphenyl)-N-(-2-methoxy-1-methylethyl)acetamide

rac-2-chloro-N-(2-ethyl-6-methylphenyl)-N-[(2R)-1-methoxypropan-2-yl]acetamide

MFCD00055293

α-Chloro-2'-ethyl-6'-methyl-N-(1-methyl-2-methoxyethyl)acetanilide

2-Chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxy-2-propanyl)acetamide

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: metolachlor [ANSI, WSSA]
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Purity: 98.0%
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: metolachlor [ANSI, WSSA]
Price: ￥178.0/1ml
Purity: 98.0%
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DC Chemicals Limited
China
Product Name: Metolachlor
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Metolachlor
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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metolachlor [ANSI, WSSA]

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