4-Methoxylonchocarpin
Modify Date: 2024-08-02 11:21:51
4-Methoxylonchocarpin structure
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Common Name | 4-Methoxylonchocarpin | ||
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| CAS Number | 51589-67-4 | Molecular Weight | 336.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H20O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 4-Methoxylonchocarpin4-Methoxylonchocarpin is an orally active anti-inflammatory agent. 4-methoxylonchocarpin inhibits the binding of LPS to Toll-like Receptor (TLR) TLR4 to inhibit NF-κB activation and TNF Receptor and IL-6 expression. 4-Methoxylonchocarpin also inhibits the phosphorylation of TGF-beta activated kinase 1 and TNBS-induced expression of IL-1β, IL-17A, and TNF. 4-methoxylonchocarpin can improve 2,4, 6-trinitrobenzene sulfonic acid (TNBS)-induced colitis mouse model[1]. |
| Name | (E)-1-(5-hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(4-methoxyphenyl)prop-2-en-1-one |
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| Synonym | More Synonyms |
| Description | 4-Methoxylonchocarpin is an orally active anti-inflammatory agent. 4-methoxylonchocarpin inhibits the binding of LPS to Toll-like Receptor (TLR) TLR4 to inhibit NF-κB activation and TNF Receptor and IL-6 expression. 4-Methoxylonchocarpin also inhibits the phosphorylation of TGF-beta activated kinase 1 and TNBS-induced expression of IL-1β, IL-17A, and TNF. 4-methoxylonchocarpin can improve 2,4, 6-trinitrobenzene sulfonic acid (TNBS)-induced colitis mouse model[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C21H20O4 |
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| Molecular Weight | 336.38 |
| Exact Mass | 336.13600 |
| PSA | 55.76000 |
| LogP | 4.48110 |
| 4-methoxylonchocarpin |
| (E)-1-(5-Hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(4-methoxy-phenyl)-propenone |
| 1-(5-hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(4-methoxyphenyl)-propenone |