N-Boc-1,5-diaminopentane structure
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Common Name | N-Boc-1,5-diaminopentane | ||
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CAS Number | 51644-96-3 | Molecular Weight | 202.294 | |
Density | 1.0±0.1 g/cm3 | Boiling Point | 309.2±25.0 °C at 760 mmHg | |
Molecular Formula | C10H22N2O2 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 140.8±23.2 °C | |
Symbol |
GHS05 |
Signal Word | Danger |
Use of N-Boc-1,5-diaminopentanePROTAC Linker 23 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 23 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Name | N-(5-Aminoamyl)Carbamic Acid Tert-Butyl Ester |
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Synonym | More Synonyms |
Description | PROTAC Linker 23 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 23 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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Related Catalog | |
Target |
Alkyl-Chain |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 309.2±25.0 °C at 760 mmHg |
Molecular Formula | C10H22N2O2 |
Molecular Weight | 202.294 |
Flash Point | 140.8±23.2 °C |
Exact Mass | 202.168121 |
PSA | 64.35000 |
LogP | 1.29 |
Vapour Pressure | 0.0±0.7 mmHg at 25°C |
Index of Refraction | 1.458 |
Storage condition | 2-8°C |
Symbol |
GHS05 |
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Signal Word | Danger |
Hazard Statements | H314 |
Precautionary Statements | P280-P305 + P351 + P338-P310 |
Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | C: Corrosive; |
Risk Phrases | R34 |
Safety Phrases | S26-S36/37/39-S45 |
RIDADR | UN 2735 8/PG 3 |
WGK Germany | 3 |
HS Code | 2924199090 |
Precursor 9 | |
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DownStream 4 | |
HS Code | 2924199090 |
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Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Structure-activity relationships among methoctramine-related polymethylene tetraamines. Chain-length and substituent effects on M-2 muscarinic receptor blocking activity.
J. Med. Chem. 32 , 79, (1989) Several polymethylene tetraamines related to methoctramine (1) were prepared and evaluated for their blocking activity on M-2 muscarinic receptors in guinea pig atria and ileum. It turned out that ant... |
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T. Teshima et al.
Tetrahedron 47 , 3305, (1991)
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V.J. Jasys et al.
J. Org. Chem. 57 , 1814, (1992)
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N-Boc-cadaverine |
N-(5-Aminopentyl)carbamic Acid tert-Butyl Ester |
tert-Butyl (5-aminopentyl)carbamate |
N-(tert-Butoxycarbonyl)-1,5-pentanediamine |
N-Boc-1,5-diaminopentane |
tert-butyl N-(5-aminopentyl)carbamate |
N-Boc-1,5-pentanediamine |
2-Methyl-2-propanyl (5-aminopentyl)carbamate |
Carbamic acid, N-(5-aminopentyl)-, 1,1-dimethylethyl ester |
N-(5-Aminoamyl)carbamic Acid tert-Butyl Ester |
MFCD00210020 |
N-(tert-Butoxycarbonyl)-1,5-diaminopentane |