Dicentrine

Modify Date: 2024-01-02 17:16:59

Dicentrine structure	Common Name	Dicentrine
	CAS Number	517-66-8	Molecular Weight	339.385
	Density	1.3±0.1 g/cm3	Boiling Point	480.7±45.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₁NO₄	Melting Point	177-178ºC
	MSDS	N/A	Flash Point	142.7±25.9 °C

Use of Dicentrine

Dicentrine is a natural product isolated from the plant Lindera megaphylla with antihypertensive effect. Dicentrine is an α1-adrenoceptor antagonist which has effective against human hyperplastic prostates[1].

Name	9,10-Dimethoxy-1,2-(methylenedioxy)aporphine
Synonym	More Synonyms

Description	Dicentrine is a natural product isolated from the plant Lindera megaphylla with antihypertensive effect. Dicentrine is an α1-adrenoceptor antagonist which has effective against human hyperplastic prostates[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	α1-adrenoceptor[1]
References	[1]. Sheu-Meei Yu, et al. Effects of dicentrine, a novel α1-adrenoceptor antagonist, on human hyperplastic prostates. European Journal of Pharmacology. 1994 Jan; 252(1):29-34.

Density	1.3±0.1 g/cm3
Boiling Point	480.7±45.0 °C at 760 mmHg
Melting Point	177-178ºC
Molecular Formula	C₂₀H₂₁NO₄
Molecular Weight	339.385
Flash Point	142.7±25.9 °C
Exact Mass	339.147064
PSA	40.16000
LogP	3.98
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.616

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CE0455000

CHEMICAL NAME :: 6a-alpha-Aporphine, 9,10-dimethoxy-1,2-(methylenedioxy)-

CAS REGISTRY NUMBER :: 517-66-8

BEILSTEIN REFERENCE NO. :: 0095476

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H21-N-O4

MOLECULAR WEIGHT :: 339.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 20 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,267,1990

(7aS)-10,11-dim...

CAS#:72203-90-8

Dicentrine

CAS#:517-66-8

Literature: Vecchietti; Casagrande; Ferrari; Severini Ricca Farmaco, Edizione Scientifica, 1979 , vol. 34, # 10 p. 829 - 840

Nordicentrine

CAS#:25394-59-6

methyl iodide

CAS#:74-88-4

Dicentrine

CAS#:517-66-8

Literature: Ghose et al. Helvetica Chimica Acta, 1934 , vol. 17, p. 919,929

diazomethane

CAS#:186581-53-3

Formaldehyde

CAS#:50-00-0

litseferine

CAS#:60142-18-9

Dicentrine

CAS#:517-66-8

Literature: Sivakumaran,M.; Gopinath,K.W. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1976 , vol. 14, p. 150 - 151

Actinodaphnine

CAS#:517-69-1

Dicentrine

CAS#:517-66-8

Literature: Ghose et al. Helvetica Chimica Acta, 1934 , vol. 17, p. 919,929

Precursor 6
CAS#:517-69-1 Actinodaphnine CAS#:25394-59-6 Nordicentrine CAS#:74-88-4 methyl iodide CAS#:186581-53-3 diazomethane
CAS#:50-00-0 Formaldehyde CAS#:60142-18-9 litseferine
DownStream 1
CAS#:19843-03-9 5H-Benzo[g]-1,3...

(7aS)-10,11-Dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline

Dicentrine

DICENTRINE- (+)

9,10-Dimethoxy-1,2-(methylenedioxy)-6aalpha-aporphine

o,N-Dimethyllitseferine

5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (S)-

d-Dicentrine

(7aS)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline

1,2-(Methylenedioxy)-9,10-dimethoxy-6aalpha-aporphine

5H-1,3-Benzodioxolo[6,5,4-de]benzo[g]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (7aS)-

1,2-Methylenedioxy-9,10-dimethoxyaporphine

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Dicentrine
Price: Negotiable
Purity: 95.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Dicentrine
Price: ￥3928.0/5mg
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Dicentrin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Dicentrine

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