OU749

Modify Date: 2024-01-07 23:20:56

OU749 Structure
OU749 structure
Common Name OU749
CAS Number 519170-13-9 Molecular Weight 361.44
Density 1.4±0.1 g/cm3 Boiling Point 565.6±52.0 °C at 760 mmHg
Molecular Formula C16H15N3O3S2 Melting Point N/A
MSDS Chinese USA Flash Point 295.9±30.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of OU749


OU749 is a potent γ-glutamyl transpeptidase (GGT) inhibitor with a Ki value of 17.6 µM. OU749 shows cytotoxicity[1].

 Names

Name N-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]benzenesulfonamide
Synonym More Synonyms

 OU749 Biological Activity

Description OU749 is a potent γ-glutamyl transpeptidase (GGT) inhibitor with a Ki value of 17.6 µM. OU749 shows cytotoxicity[1].
Related Catalog
Target

Ki: 17.6 µM (GGT)[1]

References

[1]. King JB, et al. A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase. J Biol Chem. 2009 Apr 3;284(14):9059-65.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 565.6±52.0 °C at 760 mmHg
Molecular Formula C16H15N3O3S2
Molecular Weight 361.44
Flash Point 295.9±30.7 °C
Exact Mass 361.055481
PSA 117.80000
LogP 3.04
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.644

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
RIDADR NONH for all modes of transport

 Articles1

More Articles
Crosstalk between cystine and glutathione is critical for the regulation of amino acid signaling pathways and ferroptosis.

Sci. Rep. 6 , 30033, (2016)

Although essential amino acids regulate mechanistic target of rapamycin complex 1 (mTORC1) and the integrated stress response (ISR), the role of cysteine is unknown. We found that in hepatoma HepG2 ce...

 Synonyms

Benzenesulfonamide, N-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]-
N-[5-(4-Methoxybenzyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide
OU749