Isoxanthohumol

Modify Date: 2024-01-09 20:36:44

Isoxanthohumol Structure
Isoxanthohumol structure
Common Name Isoxanthohumol
CAS Number 521-48-2 Molecular Weight 354.39600
Density N/A Boiling Point N/A
Molecular Formula C21H22O5 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Isoxanthohumol


Isoxanthohumol is a prenylflavonoid from hops and beer. Isoxanthohumol exhibits an antiproliferative activity against several human cancer cell lines. Isoxanthohumol inhibits the development of lung metastatic foci in tumor-challenged animals. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV)[1][2].

 Names

Name isoxanthohumol
Synonym More Synonyms

 Isoxanthohumol Biological Activity

Description Isoxanthohumol is a prenylflavonoid from hops and beer. Isoxanthohumol exhibits an antiproliferative activity against several human cancer cell lines. Isoxanthohumol inhibits the development of lung metastatic foci in tumor-challenged animals. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV)[1][2].
Related Catalog
Target

HSV-1

HSV-2

References

[1]. Żołnierczyk AK, et al. Isoxanthohumol--Biologically active hop flavonoid. Fitoterapia. 2015 Jun;103:71-82.

[2]. Krajnović T, et al. The hop-derived prenylflavonoid isoxanthohumol inhibits the formation of lung metastasis in B16-F10 murine melanoma model. Food Chem Toxicol. 2019 Jul;129:257-268.

 Chemical & Physical Properties

Molecular Formula C21H22O5
Molecular Weight 354.39600
Exact Mass 354.14700
PSA 75.99000
LogP 4.32160

 Safety Information

RIDADR NONH for all modes of transport
HS Code 2932999099

 Synthetic Route

~85%

Isoxanthohumol Structure

Isoxanthohumol

CAS#:521-48-2

Literature: Aniol, Miroslaw; Szymanska, Katarzyna; Zolnierczyk, Anna Tetrahedron, 2008 , vol. 64, # 40 p. 9544 - 9547

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Isoxanthohumol Structure

Isoxanthohumol

CAS#:521-48-2

Detail
Literature: Biodynamics Patent: EP1543834 A1, 2005 ; Location in patent: Page/Page column 7; 8 ;

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

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A comprehensive characterisation of beer polyphenols by high resolution mass spectrometry (LC-ESI-LTQ-Orbitrap-MS).

Food Chem. 169 , 336-43, (2014)

Beer is the second most consumed alcoholic beverage in Europe and shown by the European Prospective Investigation into Cancer and Nutrition cohort study to be the main food contributor to hydroxybenzo...

 Synonyms

4',7-DIHYDROXY-5-METHOXY-8-PRENYLFLAVANONE
Isoxanthohumol