Herbacetin
Modify Date: 2024-01-05 16:51:34
Herbacetin structure
|
Common Name | Herbacetin | ||
|---|---|---|---|---|
| CAS Number | 527-95-7 | Molecular Weight | 302.236 | |
| Density | 1.799 | Boiling Point | 618.7±55.0 °C at 760 mmHg | |
| Molecular Formula | C15H10O7 | Melting Point | 284ºC | |
| MSDS | Chinese USA | Flash Point | 239.0±25.0 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of HerbacetinHerbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects[1]. Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis[2]. |
| Name | 3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one |
|---|---|
| Synonym | More Synonyms |
| Description | Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects[1]. Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis[2]. |
|---|---|
| Related Catalog | |
| Target |
IC50: Ornithine decarboxylase[2] |
| In Vivo | Herbacetin (orally administration; 20mg/kg) significantly reduces the body weight, plasma glucose, plasma insulin, and HOMA-IR activity in obesity associated insulin resistant mice (OIR). (Herbacetin dissolves in 0.5% DMSO)[1]. Herbacetin (intraperitoneal injection; 0.4, 2, 10 or 20 mg/kg; B.W.) decreases the number and size of polyps in APCMin+ mice with no overt toxicity[2]. |
| References |
| Density | 1.799 |
|---|---|
| Boiling Point | 618.7±55.0 °C at 760 mmHg |
| Melting Point | 284ºC |
| Molecular Formula | C15H10O7 |
| Molecular Weight | 302.236 |
| Flash Point | 239.0±25.0 °C |
| Exact Mass | 302.042664 |
| PSA | 131.36000 |
| LogP | 1.14 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.823 |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| RIDADR | UN 2811 6.1 / PGIII |
| HS Code | 2914501900 |
CAS#:35815-07-7
CAS#:74137-44-3
CAS#:68385-35-3
CAS#:72055-94-8
CAS#:571-72-2
CAS#:1104525-48-5
CAS#:85734-53-8
CAS#:71468-54-7
CAS#:42923-40-0| HS Code | 2914501900 |
|---|---|
| Summary | 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
| 3,5,7,8-Tetrahydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one |
| 8-Hydroxykaempferol |
| 4H-1-Benzopyran-4-one, 3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)- |
| Herbacetin |
| 3,4',5,7,8-Pentahydroxyflavone |
| 3,4´,5,7,8-pentahydroxyflavone |
| 3,5,7,8,4'-pentahydroxyflavone |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Herbacetin
- Price: Click To Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Herbacetin
- Price: ￥2158.0/20mg
- Purity: 98.0%
- Delivery: 2 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: Herbacetin
- Price: $280.0/20mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Herbacetin
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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Price: ￥1010/1 mg
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