XIB-4035
Modify Date: 2024-01-02 15:48:57
XIB-4035 structure
|
Common Name | XIB-4035 | ||
|---|---|---|---|---|
| CAS Number | 529507-84-4 | Molecular Weight | 456.450 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 597.1±50.0 °C at 760 mmHg | |
| Molecular Formula | C26H31Cl2N3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 314.9±30.1 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of XIB-4035A nonpeptidyl small molecule agonist of GDNF family receptor α1 (GFRα-1); concentration-dependently inhibits [(125)I]GDNF binding in Neuro-2A cells with IC50 of 10.4 uM; induces autophosphorylation of Ret protein, promotes neurite outgrowth in Neuro-2A cells, and induces Ret autophosphorylation in the Neuro-2A cells. |
| Name | aminoquinol |
|---|---|
| Synonym | More Synonyms |
| Description | A nonpeptidyl small molecule agonist of GDNF family receptor α1 (GFRα-1); concentration-dependently inhibits [(125)I]GDNF binding in Neuro-2A cells with IC50 of 10.4 uM; induces autophosphorylation of Ret protein, promotes neurite outgrowth in Neuro-2A cells, and induces Ret autophosphorylation in the Neuro-2A cells. |
|---|---|
| References | References 1. Hedstrom KL, et al. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2325-30. 2. Tokugawa K, et al. Neurochem Int. 2003 Jan;42(1):81-6. 3. Höke A. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2060-1. View Related Products by Target Other Targets |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 597.1±50.0 °C at 760 mmHg |
| Molecular Formula | C26H31Cl2N3 |
| Molecular Weight | 456.450 |
| Flash Point | 314.9±30.1 °C |
| Exact Mass | 455.189514 |
| LogP | 7.69 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.650 |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H413 |
| Precautionary Statements | P301 + P310 + P330 |
| RIDADR | UN 2811 6.1 / PGIII |
| AMINOQUINOL, (R)- |
| AMINOQUINOL, (S)- |
| N4-{7-Chloro-2-[(E)-2-(2-chlorophenyl)vinyl]-4-quinolinyl}-N1,N1-diethyl-1,4-pentanediamine |
| N4-[7-Chloro-2-[(1E)-2-(2-chlorophenyl)ethenyl]-4-quinolinyl]-N1,N1-diethyl-1,4-pentanediamine |
| aminoquinol |
| MFCD00601670 |
| UNII:CH1Y88E2AY |
| 1,4-Pentanediamine, N4-[7-chloro-2-[(E)-2-(2-chlorophenyl)ethenyl]-4-quinolinyl]-N1,N1-diethyl- |
| CH1Y88E2AY |
| N4-{7-Chloro-2-[(E)-2-(2-chlorophenyl)vinyl]quinolin-4-yl}-N1,N1-diethylpentane-1,4-diamine |
| N-{7-chloro-2-[2-(2-chlorophenyl)vinyl]-4-quinolinyl}-N-[4-(diethylamino)-1-methylbutyl]amine |
| N-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quin olin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-diamine |
| XIB4035 |