Reproterol

Modify Date: 2024-01-11 16:17:07

Reproterol structure	Common Name	Reproterol
	CAS Number	54063-54-6	Molecular Weight	389.41
	Density	1.47g/cm3	Boiling Point	723.4ºC at 760mmHg
	Molecular Formula	C₁₈H₂₃N₅O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	391.3ºC

Use of Reproterol

Reproterol is a dual acting β2-adrenoceptor agonist and PDE inhibitor. The theophylline constituent of Reproterol inhibits phosphodiesterase activity induced by adenylyl cyclase. Reproterol has the potential for asthma research[1][2].

Name	7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-1,3-dimethylpurine-2,6-dione
Synonym	More Synonyms

Description	Reproterol is a dual acting β2-adrenoceptor agonist and PDE inhibitor. The theophylline constituent of Reproterol inhibits phosphodiesterase activity induced by adenylyl cyclase. Reproterol has the potential for asthma research[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Inflammation/Immunology
Target	β2 adrenoceptor
References	[1]. Uwe R Juergens, et al. Different mechanisms of action of beta2-adrenergic receptor agonists: a comparison of reproterol, fenoterol and salbutamol on monocyte cyclic-AMP and leukotriene B4 production in vitro. Eur J Med Res. 2004 Jul 30;9(7):365-70. [2]. C G Georgakopoulos, et al. Excretion study of the beta2-agonist reproterol in human urine. J Chromatogr B Biomed Sci Appl. 1999 Apr 16;726(1-2):141-8.

Density	1.47g/cm3
Boiling Point	723.4ºC at 760mmHg
Molecular Formula	C₁₈H₂₃N₅O₅
Molecular Weight	389.41
Flash Point	391.3ºC
Exact Mass	389.17000
PSA	134.54000

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XH5098950

CHEMICAL NAME :: Theophylline, 7-(3-((2-(3,5-dihydroxyphenyl)-2-hydroxyethyl)amino)p ropyl)-

CAS REGISTRY NUMBER :: 54063-54-6

BEILSTEIN REFERENCE NO. :: 0590567

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H23-N5-O5

MOLECULAR WEIGHT :: 389.46

WISWESSER LINE NOTATION :: T56 BN DN FNVNVJ B3N2QR CQ EQ& F1 H1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 145 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,14,1977

Reproterol [INN:BAN]

EINECS 258-956-1

7-{3-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethylamino]-propyl}-1,3-dimethyl-3,7-dihydro-purine-2,6-dione

7-{3-[2-(3,5-dihydroxyphenyl)-2-hydroxyethylamino]-propyl}-theophylline

Theophylline,7-(3-((2-(3,5-dihydroxyphenyl)-2-hydroxyethyl)amino)propyl)

Reproterolum [INN-Latin]

7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione

7-<3-<2-(3,5-dihydroxyphenyl)-2-hydroxyethylamino>propyl>-theophyllin

D 1959

Reproterol

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Reproterol
Price: Click To Check
Purity: 96.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Reproterol
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Reproterol

Use of Reproterol

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Reproterol Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synonyms