Vacquinol-1

Modify Date: 2024-01-05 17:51:37

Vacquinol-1 Structure
Vacquinol-1 structure
Common Name Vacquinol-1
CAS Number 5428-80-8 Molecular Weight 352.857
Density 1.2±0.1 g/cm3 Boiling Point 551.4±50.0 °C at 760 mmHg
Molecular Formula C21H21ClN2O Melting Point N/A
MSDS N/A Flash Point 287.3±30.1 °C

 Use of Vacquinol-1


Vacquinol-1 (NSC13316) is a MKK4-specific activator that activates MAPK pathways[1]. Vacquinol-1 specifically induces human glioblastoma cell (GC) death, attenuates tumor progression and prolongs survival in a glioblastoma multiforme (GBM) mouse model[2]. Vacquinol-1 also induces apoptosis in hepatocellular carcinoma (HCC)cell[3].

 Names

Name [2-(4-chlorophenyl)quinolin-4-yl]-piperidin-2-ylmethanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 551.4±50.0 °C at 760 mmHg
Molecular Formula C21H21ClN2O
Molecular Weight 352.857
Flash Point 287.3±30.1 °C
Exact Mass 352.134247
PSA 45.15000
LogP 3.87
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.643
Storage condition -20℃

 Safety Information

HS Code 2933990090

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(2-(4-chlorophenyl)-4-quinolinyl)(2-piperidinyl)methanol
4-Quinolinemethanol, 2-(4-chlorophenyl)-α-2-piperidinyl-
[2-(4-chlorophenyl)quinolin-4-yl](piperidin-2-yl)methanol
[2-(4-chloro-phenyl)-[4]quinolyl]-[2]piperidyl-methanol
[2-(4-Chlor-phenyl)-[4]chinolyl]-[2]piperidyl-methanol
[2-(4-Chlorophenyl)-4-quinolinyl](2-piperidinyl)methanol
Vacquinol-1
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