Trihydroxycholestanoic Acid

Modify Date: 2024-01-29 10:54:37

Trihydroxycholestanoic Acid Structure
Trihydroxycholestanoic Acid structure
Common Name Trihydroxycholestanoic Acid
CAS Number 547-98-8 Molecular Weight 450.65100
Density N/A Boiling Point N/A
Molecular Formula C27H46O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Trihydroxycholestanoic Acid


Trihydroxycholestanoic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Refsum Disease, D Bifunctional Protein Deficiency and Infantile Refsum Disease[1][2][3][4].

 Names

Name 3α,7α,12α-trihydroxy-5β-cholestan-26-oic acid
Synonym More Synonyms

 Trihydroxycholestanoic Acid Biological Activity

Description Trihydroxycholestanoic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Refsum Disease, D Bifunctional Protein Deficiency and Infantile Refsum Disease[1][2][3][4].
Related Catalog
In Vitro Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
References

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.  

[2]. Baumgartner MR, et al. Clinical approach to inherited peroxisomal disorders: a series of 27 patients. Ann Neurol. 1998 Nov;44(5):720-30.  

[3]. Poll-The BT, et al. Infantile Refsum's disease: biochemical findings suggesting multiple peroxisomal dysfunction. J Inherit Metab Dis. 1986;9(2):169-74.  

[4]. Rizzo C, et al. Characteristic acylcarnitine profiles in inherited defects of peroxisome biogenesis: a novel tool for screening diagnosis using tandem mass spectrometry. Pediatr Res. 2003 Jun;53(6):1013-8.  

 Chemical & Physical Properties

Molecular Formula C27H46O5
Molecular Weight 450.65100
Exact Mass 450.33500
PSA 97.99000
LogP 4.47490

 Precursor & DownStream

Precursor  0

DownStream  2

 Synonyms

3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oic acid
Trihydroxycholestanoic acid
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