547-98-8

547-98-8 structure

Name: Trihydroxycholestanoic Acid
Chemical Name: 3α,7α,12α-trihydroxy-5β-cholestan-26-oic acid
CAS Number: 547-98-8
Molecular Formula: C₂₇H₄₆O₅
Molecular Weight: 450.65100
Catalog: Research Areas Inflammation/Immunology
Create Date: 2017-03-08 13:45:33
Modify Date: 2024-01-29 10:54:37
Trihydroxycholestanoic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Refsum Disease, D Bifunctional Protein Deficiency and Infantile Refsum Disease[1][2][3][4].

Name	3α,7α,12α-trihydroxy-5β-cholestan-26-oic acid
Synonyms	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oic acid Trihydroxycholestanoic acid

Description	Trihydroxycholestanoic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Refsum Disease, D Bifunctional Protein Deficiency and Infantile Refsum Disease[1][2][3][4].
Related Catalog	Research Areas >> Inflammation/Immunology
In Vitro	Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
References	[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720. [2]. Baumgartner MR, et al. Clinical approach to inherited peroxisomal disorders: a series of 27 patients. Ann Neurol. 1998 Nov;44(5):720-30. [3]. Poll-The BT, et al. Infantile Refsum's disease: biochemical findings suggesting multiple peroxisomal dysfunction. J Inherit Metab Dis. 1986;9(2):169-74. [4]. Rizzo C, et al. Characteristic acylcarnitine profiles in inherited defects of peroxisome biogenesis: a novel tool for screening diagnosis using tandem mass spectrometry. Pediatr Res. 2003 Jun;53(6):1013-8.

Precursor 0
DownStream 2
81-25-4 17974-66-2